Evidence map›Paper›PMID 27965593›Full record

ReviewFrontiers in physiology2016

The Cu, Zn Superoxide Dismutase: Not Only a Dismutase Enzyme.

Paolo Mondola, Simona Damiano, Anna Sasso, Mariarosaria Santillo

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06342024 (Effects of Pistachio Consumption on Inflammatory Markers and Lean Body Mass in Recreationally Active Women and Men), which is not on this map. Cited by 83 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06342024 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Effects of Pistachio Consumption on Inflammatory Markers and Lean Body Mass in Recreationally Active Women and Men

TypeinterventionalSponsorVirginia Polytechnic Institute and State UniversityRan2024 to 2026Enrolled144ConditionsInflammatory ResponseArmsPistachio group
3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 1 synthesis or guideline pooled it, 156 citations in OpenAlex.

  1. Pooled it
  2. Clinical translation and landscape of copper nanoparticles.Drug delivery and translational research · 2026
    Review
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  10. Copper homeostasis and cuproptosis in Alzheimer's disease (Review).International journal of molecular medicine · 2025
    Review
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Paolo MondolaDipartimento di Medicina Clinica e Chirurgia, Unità di Fisiologia Umana, Università degli Studi di Napoli "Federico II," Napoli, Italy.
Simona DamianoDipartimento di Medicina Clinica e Chirurgia, Unità di Fisiologia Umana, Università degli Studi di Napoli "Federico II," Napoli, Italy.
Anna SassoDipartimento di Medicina Clinica e Chirurgia, Unità di Fisiologia Umana, Università degli Studi di Napoli "Federico II," Napoli, Italy.
Mariarosaria SantilloDipartimento di Medicina Clinica e Chirurgia, Unità di Fisiologia Umana, Università degli Studi di Napoli "Federico II," Napoli, Italy.
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Cu,Zn superoxide dismutase (SOD1) is an ubiquitary cytosolic dimeric carbohydrate free molecule, belonging to a family of isoenzymes involved in the scavenger of superoxide anions. This effect certainly represents the main and well known function ascribed to this enzyme. Here we highlight new aspects of SOD1 physiology that point out some inedited effects of this enzyme in addition to the canonic role of oxygen radical enzymatic dismutation. In the last two decades our research group produced many data obtained in

Indexed as

CuZn superoxide dismutasemuscarinic M1 receptoroxidative stresssecretiontransductional mechanisms

Identifiers

PMID27965593
PMCPMC5126113
OpenAlexW2558473568

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.