Evidence map›Paper›PMID 27965544›Full record

ArticleFrontiers in neural circuits2016

An Exploratory Study of Spectroscopic Glutamatergic Correlates of Cortical Excitability in Depressed Adolescents.

Charles P Lewis, John D Port, Mark A Frye, Jennifer L Vande Voort, Stephanie H Ameis, Mustafa M Husain, Zafiris J Daskalakis, Paul E Croarkin

2 registry-linked trialsOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neural circuits, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03840369 nacompletednot on this mapstarted 2020, after this paper: background citation

Pathophysiological Understanding and Treatment of PTSD: an rTMS Approach

TypeinterventionalSponsorUniversity of CalgaryRan2020 to 2022Enrolled25ConditionsStress Disorders, Post-Traumatic, Brain Injuries, Transcranial Magnetic Stimulation, Magnetic Resonance SpectroscopyArmsRepetitive Transcranial Magnetic Stimulation to Right Dorsolateral Prefrontal Cortex, Sham Repetitive Transcranial Magnetic Stimulation, Repetitive Transcranial Magnetic Stimulation to Right Dorsomedial Prefrontal Cortex
NCT04568369 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Functional Near Infrared Spectroscopy as a Biomarker of Response in Patients With Post-concussion Syndrome Treated With Transcranial Magnetic Stimulation

TypeinterventionalSponsorUniversity of CalgaryRan2020 to 2024Enrolled91ConditionsTranscranial Magnetic Stimulation, Functional Near-Infrared Spectroscopy, Post-Concussion Syndrome, ConcussionArmsrTMS
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. A pilot spectroscopy study of adversity in adolescents.Biomarkers in neuropsychiatry · 2021
    Article
  5. Article
  6. Transcranial Magnetic Stimulation for Adolescent Depression.Child and adolescent psychiatric clinics of North America · 2019
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Charles P LewisMayo Clinic Depression Center, Department of Psychiatry and Psychology, Mayo Clinic Rochester, MN, USA.
John D PortMayo Clinic Depression Center, Department of Psychiatry and Psychology, Mayo ClinicRochester, MN, USA; Department of Radiology, Mayo ClinicRochester, MN, USA.
Mark A FryeMayo Clinic Depression Center, Department of Psychiatry and Psychology, Mayo Clinic Rochester, MN, USA.
Jennifer L Vande VoortMayo Clinic Depression Center, Department of Psychiatry and Psychology, Mayo Clinic Rochester, MN, USA.
Stephanie H AmeisFaculty of Medicine, Department of Psychiatry, University of TorontoToronto, ON, Canada; Temerty Centre for Therapeutic Brain Intervention, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, University of TorontoToronto, ON, Canada; The Margaret and Wallace McCain Centre for Child, Youth and Family Mental Health, Campbell Family Mental Health Research Institute, The Centre for Addiction and Mental Health, University of TorontoToronto, ON, Canada.
Mustafa M HusainDepartment of Psychiatry, University of Texas Southwestern Medical CenterDallas, TX, USA; Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical CenterDallas, TX, USA; Department of Psychiatry and Behavioral Sciences, Duke University School of MedicineDurham, NC, USA.
Zafiris J DaskalakisFaculty of Medicine, Department of Psychiatry, University of TorontoToronto, ON, Canada; Temerty Centre for Therapeutic Brain Intervention, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, University of TorontoToronto, ON, Canada.
Paul E CroarkinMayo Clinic Depression Center, Department of Psychiatry and Psychology, Mayo Clinic Rochester, MN, USA.
Mayo Clinic in Arizona · USCentre for Addiction and Mental Health · CADuke University · USUniversity of Toronto · CA

Funding

Glutamate Probes in Adolescent DepressionK23MH100266 · NIMH · MAYO CLINIC ROCHESTER · PI CROARKIN, PAUL E · 2014 to 2017
$685k
NIMH NIH HHS K23 MH100266
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Depressive DisorderGyrus CinguliMotor CortexAdolescentChildEvoked Potentials, MotorFemaleGlutamic AcidGlutamineHumansMagnetic Resonance SpectroscopyMaleNeural InhibitionTranscranial Magnetic StimulationGlutamic AcidGlutaminechild and adolescentcortical excitabilitydepressionglutamateproton magnetic resonance spectroscopytranscranial magnetic stimulation

Identifiers

PMID27965544
PMCPMC5127083
OpenAlexW2558509976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.