ArticleBMJ open2016
Gender disparities in red blood cell transfusion in elective surgery: a post hoc multicentre cohort study.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 45 citations in OpenAlex.
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- Differential associations between preoperative anaemia and postoperative outcomes in women and men undergoing surgeryBritish journal of anaesthesia · 2026Observational
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- Modified Del Nido "microplegia" reduces intraoperative, postoperative, and total blood products.JTCVS open · 2026Article
- Blood transfusion and mortality after spine osteotomy: a nationwide population-based retrospective cohort study.Scientific reports · 2025Article
- The Seroprevalence, Risk Factors, and Clinical Profile of Hepatitis D in Omani Patients with Chronic Hepatitis B: A Multicenter Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Return on Investment of Preoperative Anemia Management Programs in Cardiac Surgery: An Advisory From the Society of Cardiovascular Anesthesiologists Clinical Practice Improvement Committee With Endorsement by the Society for the Advancement of Patient Blood Management.Anesthesia and analgesia · 2024Article
- Do Patients with Borderline Anemia Need Treatment before Total Hip Arthroplasty? A Propensity Score-Matched Cohort Study.Orthopaedic surgery · 2024Article
- Sex Differences in Red Blood Cell Transfusions and 30-Day Mortality in Cardiac Surgery: A Single Center Observational Study.Journal of clinical medicine · 2023Article
- Epidemiology and Associated Factors in Transfusion Management in Intensive Care Unit.Journal of clinical medicine · 2022Article
- Blood transfusion risk prediction in spinal tuberculosis surgery: development and assessment of a novel predictive nomogram.BMC musculoskeletal disorders · 2022Article
- Preoperative patient factors associated with blood product use in cardiac surgery, a retrospective cohort study.Journal of cardiothoracic surgery · 2022Article
- Impact of gender parity on preoperative anaemia prevalence and Patient Blood Management practice.Blood transfusion = Trasfusione del sangue · 2021Article
- Predictors for Perioperative Blood Transfusion in Patients Undergoing Open Cystectomy and Urinary Diversion and Development of a Nomogram: An Observational Cohort Study.Journal of clinical medicine · 2021Article
- Treatment of Anaemia in Patients with Acute Burn Injury: A Study of Blood Transfusion Practices.Journal of clinical medicine · 2021Article
- Perioperative Transfusions for Gastroesophageal Cancers: Risk Factors and Short- and Long-Term Outcomes.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Article
- Lower preoperative hematocrit, longer hospital stay, and neurocognitive decline after cardiac surgery.Surgery · 2020Article
- Influence of factor XIII activity on post-operative transfusion in congenital cardiac surgery-A retrospective analysis.PloS one · 2018Article
- Development of Multivariable Models to Predict and Benchmark Transfusion in Elective Surgery Supporting Patient Blood Management.Applied clinical informatics · 2017Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesA post hoc gender comparison of transfusion-related modifiable risk factors among patients undergoing elective surgery. SETTINGS: 23 Austrian centres randomly selected and stratified by region and level of care.
participantsWe consecutively enrolled in total 6530 patients (3465 women and 3065 men); 1491 underwent coronary artery bypass graft (CABG) surgery, 2570 primary unilateral total hip replacement (THR) and 2469 primary unilateral total knee replacement (TKR).
main outcome measuresPrimary outcome measures were the number of allogeneic and autologous red blood cell (RBC) units transfused (postoperative day 5 included) and differences in intraoperative and postoperative transfusion rate between men and women. Secondary outcomes included perioperative blood loss in transfused and non-transfused patients, volume of RBCs transfused, perioperative haemoglobin values and circulating red blood volume on postoperative day 5.
resultsIn all surgical groups, the transfusion rate was significantly higher in women than in men (CABG 81 vs 49%, THR 46 vs 24% and TKR 37 vs 23%). In transfused patients, the absolute blood loss was higher among men in all surgical categories while the relative blood loss was higher among women in the CABG group (52.8 vs 47.8%) but comparable in orthopaedic surgery. The relative RBC volume transfused was significantly higher among women in all categories (CABG 40.0 vs 22.3; TKR 25.2 vs 20.2; THR 26.4 vs 20.8%). On postoperative day 5, the relative haemoglobin values and the relative circulating RBC volume were higher in women in all surgical categories.
conclusionsThe higher transfusion rate and volume in women when compared with men in elective surgery can be explained by clinicians applying the same absolute transfusion thresholds irrespective of a patient's gender. This, together with the common use of a liberal transfusion strategy, leads to further overtransfusion in women.
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