Evidence map›Paper›PMID 27965180›Full record

Trial reportContemporary clinical trials2017

A randomized controlled trial of a community health worker intervention in a population of patients with multiple chronic diseases: Study design and protocol.

Shreya Kangovi, Nandita Mitra, Lindsey Turr, Hairong Huo, David Grande, Judith A Long

2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01900470 nacompletednot on this map

Community Health Worker Support to Help Patients Control Chronic Disease

TypeinterventionalSponsorUniversity of PennsylvaniaRan2013 to 2017Enrolled302ConditionsObesity, Diabetes, Hypertension, Asthma/COPD With Tobacco DependenceArmsCHW Goal Support
NCT07279415 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Activate Tennessee: A CHW-Supported Program for Patient Activation

TypeinterventionalSponsorMeharry Medical CollegeRan2025 to 2027Enrolled300ConditionsDiabetes, Hypertension, Cardio Vascular Disease, Infectious Diseases MorbidityArmsIntervention, Control Group
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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  16. Estimating scaled treatment effects with multiple outcomes.Statistical methods in medical research · 2019
    Article
  17. Article
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  19. Health Equity Considerations in State Bills Related to Doula Care (2015-2020).Women's health issues : official publication of the Jacobs Institute of Women's Health
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shreya KangoviPerelman School of Medicine, University of Pennsylvania, Division of General Internal Medicine, Philadelphia 19104, PA, United States; Penn Center for Community Health Workers, Penn Medicine, Philadelphia 19104, PA, United States. Electronic address: kangovi@mail.med.upenn.edu.
Nandita MitraPerelman School of Medicine, University of Pennsylvania, Department of Biostatistics and Epidemiology, Philadelphia 19104, PA, United States. Electronic address: nanditam@mail.med.upenn.edu.
Lindsey TurrPerelman School of Medicine, University of Pennsylvania, Division of General Internal Medicine, Philadelphia 19104, PA, United States. Electronic address: lindsey.turr@uphs.upenn.edu.
Hairong HuoPerelman School of Medicine, University of Pennsylvania, Division of General Internal Medicine, Philadelphia 19104, PA, United States. Electronic address: huoh@mail.med.upenn.edu.
David GrandePerelman School of Medicine, University of Pennsylvania, Division of General Internal Medicine, Philadelphia 19104, PA, United States. Electronic address: dgrande@wharton.upenn.edu.
Judith A LongPerelman School of Medicine, University of Pennsylvania, Division of General Internal Medicine, Philadelphia 19104, PA, United States; Center for Health Equity Research and Promotion, Corporal Michael J. Crescenz VA, Philadelphia 19104, PA, United States. Electronic address: jalong@mail.med.upenn.edu.
University of Pennsylvania · US

Funding

Modifying Behavioral Response to Failure among Patients with Cardiovascular Disease Risk FactorsK23HL128837 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KANGOVI, SHREYA · 2016 to 2019
$695k
NHLBI NIH HHS K23 HL128837
6 · The paper itself

Abstract

Upstream interventions - e.g. housing programs and community health worker interventions- address socioeconomic and behavioral factors that influence health outcomes across diseases. Studying these types of interventions in clinical trials raises a methodological challenge: how should researchers measure the effect of an upstream intervention in a sample of patients with different diseases? This paper addresses this question using an illustrative protocol of a randomized controlled trial of collaborative-goal setting versus goal-setting plus community health worker support among patients multiple chronic diseases: diabetes, obesity, hypertension and tobacco dependence. At study enrollment, patients met with their primary care providers to select one of their chronic diseases to focus on during the study, and to collaboratively set a goal for that disease. Patients randomly assigned to a community health worker also received six months of support to address socioeconomic and behavioral barriers to chronic disease control. The primary hypothesis was that there would be differences in patients' selected chronic disease control as measured by HbA1c, body mass index, systolic blood pressure and cigarettes per day, between the goal-setting alone and community health worker support arms. To test this hypothesis, we will conduct a stratum specific multivariate analysis of variance which allows all patients (regardless of their selected chronic disease) to be included in a single model for the primary outcome. Population health researchers can use this approach to measure clinical outcomes across diseases. CLINICAL TRIALS REGISTRATION: ClinicalTrials.gov Identifier: NCT01900470.

Indexed as

Community Health WorkersSocial Determinants of HealthDiabetes MellitusDisease ManagementGoalsHumansHypertensionMultiple Chronic ConditionsObesityPatient Care PlanningSocial SupportTobacco Use DisorderRandomized controlled trialSocioeconomic determinantsUpstream medicine

Identifiers

PMID27965180
PMCPMC5455773
OpenAlexW2560671754

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.