ArticleNano letters2016
Nanodiamond-Gadolinium(III) Aggregates for Tracking Cancer Growth In Vivo at High Field.
Article in Nano letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Clinical validation of a nanodiamond-embedded thermoplastic biomaterial.Proceedings of the National Academy of Sciences of the United States of America · 2017Trial
- Convergent Evolution: Self-Assembly of Small Molecule, Polymeric, and Inorganic Contrast Agents toward Advanced MRI.Journal of the American Chemical Society · 2025Review
- Alkaline Phosphatase-Targeted, Gadolinium-Labeled Nanoparticles for Enhanced Multimodal Imaging of Liver Cancer.ACS applied materials & interfaces · 2025Article
- XPS Study of Grafting Paramagnetic Ions onto the Surface of Detonation Nanodiamonds.Nanomaterials (Basel, Switzerland) · 2025Article
- Recent Advances on Pt-Based Compounds for Theranostic Applications.Molecules (Basel, Switzerland) · 2024Review
- A Review on the Design of Carbon-Based Nanomaterials as MRI Contrast Agents.Molecules (Basel, Switzerland) · 2024Review
- Production, surface modification, physicochemical properties, biocompatibility, and bioimaging applications of nanodiamonds.RSC advances · 2023Review
- Rare-earth hydroxide/MXene hybrid: a promising agent for near-infrared photothermy and magnetic resonance imaging.Chemical science · 2023Article
- Engineered Nonviral Protein Cages Modified for MR Imaging.ACS applied bio materials · 2023Article
- Article
- Recent Development of Fluorescent Nanodiamonds for Optical Biosensing and Disease Diagnosis.Biosensors · 2022Review
- Revisiting the factors influencing the magnetic resonance contrast of GdNanoscale advances · 2021Article
- Nanoparticles as a Tool in Neuro-Oncology Theranostics.Pharmaceutics · 2021Review
- Artificially engineered antiferromagnetic nanoprobes for ultra-sensitive histopathological level magnetic resonance imaging.Nature communications · 2021Article
- Origin of the MRI Contrast in Natural and Hydrogel Formulation of Pineapple Juice.Bioinorganic chemistry and applications · 2021Article
- Revisiting paramagnetic relaxation enhancements in slowly rotating systems: how long is the long range?Magnetic resonance (Gottingen, Germany) · 2021Article
- Examining relaxivities in suspensions of nanodiamonds grafted by magnetic entities: comparison of two approaches.Magma (New York, N.Y.) · 2020Article
- Gadolinium-containing carbon nanomaterials for magnetic resonance imaging: Trends and challenges.Journal of cellular and molecular medicine · 2020Review
- Gd(iii)-Pt(iv) theranostic contrast agents for tandem MR imaging and chemotherapy.Chemical science · 2020Article
- Water-Soluble Nanoconjugate for Enhanced Cellular Delivery of Receptor-Targeted Magnetic Resonance Contrast Agents.Bioconjugate chemistry · 2019Article
Corrections and comments
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Authors and funding
13 authors.
Funding
Abstract
The ability to track labeled cancer cells in vivo would allow researchers to study their distribution, growth, and metastatic potential within the intact organism. Magnetic resonance (MR) imaging is invaluable for tracking cancer cells in vivo as it benefits from high spatial resolution and the absence of ionizing radiation. However, many MR contrast agents (CAs) required to label cells either do not significantly accumulate in cells or are not biologically compatible for translational studies. We have developed carbon-based nanodiamond-gadolinium(III) aggregates (NDG) for MR imaging that demonstrated remarkable properties for cell tracking in vivo. First, NDG had high relaxivity independent of field strength, a finding unprecedented for gadolinium(III) [Gd(III)]-nanoparticle conjugates. Second, NDG demonstrated a 300-fold increase in the cellular delivery of Gd(III) compared to that of clinical Gd(III) chelates without sacrificing biocompatibility. Further, we were able to monitor the tumor growth of NDG-labeled flank tumors by T
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.