Evidence map›Paper›PMID 27959866›Full record

ArticleAging2016

Quiescin-sulfhydryl oxidase inhibits prion formation

Yi-An Zhan, Romany Abskharon, Yu Li, Jue Yuan, Liang Zeng, Johnny Dang, Manuel Camacho Martinez, Zerui Wang, Jacqueline Mikol, Sylvain Lehmann and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 5 countries.

Yi-An ZhanFirst Affiliated Hospital, Nanchang University, Nanchang, Jiangxi Province, The People's Republic of China.
Romany AbskharonVIB Center for Structural Biology, VIB, 1050 Brussels, Belgium.
Yu LiFirst Affiliated Hospital, Nanchang University, Nanchang, Jiangxi Province, The People's Republic of China.
Jue YuanDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Liang ZengFirst Affiliated Hospital, Nanchang University, Nanchang, Jiangxi Province, The People's Republic of China.
Johnny DangDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Manuel Camacho MartinezDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Zerui WangDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Jacqueline MikolHôpital Lariboisière, Service d'Anatomie et Cytologie Pathologiques, Paris, France.
Sylvain LehmannIRMB -Hôpital ST ELOI, CHU de Montpellier, Montpellier, France.
Shizhong BuDiabetes Research Center, Ningbo University, The People's Republic of China.
Jan SteyaertVIB Center for Structural Biology, VIB, 1050 Brussels, Belgium.
Li CuiDepartment of Neurology, The First Hospital of Jilin University, Changchun, Jilin Province, The People's Republic of China.
Robert B PetersenDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Qingzhong KongDepartment of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Gong-Xiang WangFirst Affiliated Hospital, Nanchang University, Nanchang, Jiangxi Province, The People's Republic of China.
Alexandre WohlkonigVIB Center for Structural Biology, VIB, 1050 Brussels, Belgium.
Wen-Quan ZouFirst Affiliated Hospital, Nanchang University, Nanchang, Jiangxi Province, The People's Republic of China.
Case Western Reserve University · USUniversity School · USNanchang University · CNVrije Universiteit Brussel · BEFirst Hospital of Jilin University · CNHôpital Lariboisière · FRHôpital Saint Eloi · FRNingbo University · CNVIB-VUB Center for Structural Biology · BE

Funding

Assessing the Transmissibility of CWD to HumansR01NS052319 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI KONG, QINGZHONG · 2006 to 2010
$1.7M
Pathogenicity of prion protein aggregates from uninfected cells and brainsR01NS062787 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI ZOU, WEN-QUAN · 2009 to 2013
$1.4M
Cervid to human prion transmissionR01NS088604 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI KONG, QINGZHONG · 2015 to 2018
$1.4M
Generating iPSC-derived Neurons to Explore Formation & Inhibition of Human PrionsR21NS087588 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI QI, XIN, TESAR, PAUL JOSEPH · 2014 to 2015
$436k
Accessing transmissibility and diagnostic marker of skin prions.R21NS096626 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI KONG, QINGZHONG, SAFAR, JIRI G. · 2016 to 2017
$436k
NINDS NIH HHS R01 NS052319NINDS NIH HHS R01 NS062787NINDS NIH HHS R01 NS088604NINDS NIH HHS R21 NS087588NINDS NIH HHS R21 NS096626
6 · The paper itself

Abstract

Prions are infectious proteins that cause a group of fatal transmissible diseases in animals and humans. The scrapie isoform (PrP

Indexed as

AnimalsBrainCell Line, TumorHumansMiceNeuroblastomaOxidoreductasesOxidoreductases Acting on Sulfur Group DonorsPrionsProtein FoldingScrapieOxidoreductasesOxidoreductases Acting on Sulfur Group DonorsPrionsprionsprotein misfolding cyclic amplificationQuiescin sulfhydryl oxidase (QSOX)recombinant prion proteinscrapie-infected mouse neuroblastoma cells (ScN2a)

Identifiers

PMID27959866
PMCPMC5270677
OpenAlexW2565545769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.