Evidence map›Paper›PMID 27959686›Full record

ArticleThe New England journal of medicine2016

Efficacy of Convalescent Plasma in Relation to Dose of Ebola Virus Antibodies.

Johan van Griensven, Tansy Edwards, Sylvain Baize, Ebola-Tx Consortium

3 registry-linked trialsAbstract readLetterComment
In one paragraph

Article in The New England journal of medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02342171 phase2 / phase3completednot on this map

Emergency Evaluation of Convalescent Plasma for Ebola Viral Disease (EVD) in Guinea

TypeinterventionalSponsorInstitute of Tropical Medicine, BelgiumRan2015 to 2015Enrolled606ConditionsHemorrhagic Fever, EbolaArmsConvalescent Plasma
NCT04395170 phase2 / phase3unknown statusnot on this mapstarted 2020, after this paper: background citation

A Randomized, Multicenter Clinical Trial to Evaluate the Efficacy and Safety of the Use of Convalescent Plasma (PC) and Human Intravenous Anti COVID-19 Immunoglobulin (IV Anti COVID-19 IgG) in Patients Hospitalized for COVID-19.

TypeinterventionalSponsorLifefactors Zona Franca, SASRan2020 to 2021Enrolled75ConditionsCoronavirus Disease 2019 (COVID-19)ArmsCOVID-19 convalescent plasma, Anti-COVID-19 human immunoglobulin, Standard (specific) therapy for COVID-19
NCT04502472 phase2 / phase3terminatednot on this mapstarted 2020, after this paper: background citation

Treatment of Severe Coronavirus Disease 2019 (COVID-19) With Convalescent Plasma Collected From Individuals With Documented Infection and Recovery From COVID-19 (SARS-CoV-2)

TypeinterventionalSponsorInova Health Care ServicesRan2020 to 2020Enrolled109ConditionsCovid-19ArmsConvalescent plasma transfusion
3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Effectiveness and safety of available treatments for COVID-19 during pregnancy: a critical review.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2022
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. A Forgotten Episode of Marburg Virus Disease: Belgrade, Yugoslavia, 1967.Microbiology and molecular biology reviews : MMBR · 2020
    Review
  14. Article
  15. Ebola virus disease.Nature reviews. Disease primers · 2020
    Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Johan van GriensvenInstitute of Tropical Medicine, Antwerp, Belgium jvangriensven@itg.be.
Tansy EdwardsLondon School of Hygiene and Tropical Medicine, London, United Kingdom.
Sylvain BaizeInstitut Pasteur, Lyon, France.
Ebola-Tx Consortium

Funding

Medical Research Council MR/K012126/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, ViralEbolavirusHemorrhagic Fever, EbolaPlasmaAntibodies, Viral

Identifiers

PMID27959686
PMCPMC5833944

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.