Evidence map›Paper›PMID 27959616›Full record

ReviewAnnual review of physiology2017

Coronary Artery Development: Progenitor Cells and Differentiation Pathways.

Bikram Sharma, Andrew Chang, Kristy Red-Horse

Abstract readReview
In one paragraph

Review in Annual review of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Trial
  2. Article
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  4. Review
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  6. Review
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  11. Hypoxia regulate developmental coronary angiogenesis potentially through VEGF-R2- and SOX17-mediated signaling.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Congenital Coronary Artery Anomalies.Journal of the Korean Society of Radiology · 2024
    Article
  19. Article
  20. Human Cardiac Development.Advances in experimental medicine and biology · 2024
    Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bikram SharmaDepartment of Biology, Stanford University, Stanford, California 94305; email: kredhors@stanford.edu.
Andrew ChangDepartment of Biology, Stanford University, Stanford, California 94305; email: kredhors@stanford.edu.
Kristy Red-HorseDepartment of Biology, Stanford University, Stanford, California 94305; email: kredhors@stanford.edu.

Funding

Mechanotransduction and transcriptional regulation during artery developmentR01HL128503 · NHLBI · STANFORD UNIVERSITY · PI Mary Red-Horse · 2015 to 2026
$5.8M
NHLBI NIH HHS R01 HL128503
6 · The paper itself

Abstract

Coronary artery disease (CAD) is the number one cause of death worldwide and involves the accumulation of plaques within the artery wall that can occlude blood flow to the heart and cause myocardial infarction. The high mortality associated with CAD makes the development of medical interventions that repair and replace diseased arteries a high priority for the cardiovascular research community. Advancements in arterial regenerative medicine could benefit from a detailed understanding of coronary artery development during embryogenesis and of how these pathways might be reignited during disease. Recent research has advanced our knowledge on how the coronary vasculature is built and revealed unexpected features of progenitor cell deployment that may have implications for organogenesis in general. Here, we highlight these recent findings and discuss how they set the stage to interrogate developmental pathways during injury and disease.

Indexed as

AnimalsCell DifferentiationCoronary Artery DiseaseCoronary VesselsHeartHumansOrganogenesisStem Cellsblood flowcoronary arteryendocardiumsinus venosusvascular remodeling

Identifiers

PMID27959616
PMCPMC5513160

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.