ArticleThe ISME journal2017
New roles in hemicellulosic sugar fermentation for the uncultivated Bacteroidetes family BS11.
Article in The ISME journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
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Who cites it
75 citing papers in PubMed, 145 citations in OpenAlex.
- Rumen Microbiota, Predicted Metabolic Pathways, and Fermentation Parameters Exhibit Production-System-Specific Associations in Cattle and Goats.Microorganisms · 2026Article
- d-lactate drives lysine d-lactylation to regulate metabolism in Escherichia coli.The Journal of biological chemistry · 2026Article
- Genome-resolved multi-omics provide new insights into microbial nitrogen utilization by the rumen microbiota.Microbiome · 2026Article
- Different combinations of lignocellulolytic enzymes and lactic acid bacteria affect the quality and aerobic stability of rain-soaked Sudan grass silage by regulating the silage microbial community.Microbiology spectrum · 2026Article
- Lyophilized rumen fluid from goats fed different roughage-based diets: fermentation characteristics, microbial communities, and post-reconstitutionFrontiers in microbiology · 2026Article
- Assembly Patterns and Functional Roles of Bacterial Generalists and Specialists in the Remediation of Saline-Alkali Soils.Environmental microbiology reports · 2025Article
- Whole-Genome Sequence Reveals Genetic Determinants of the Colonization of Shiga Toxin-Producing Escherichia coli O22:H8 Isolates in Cattle.Current microbiology · 2025Article
- Article
- Degradability, rumen fermentation, and rumen microbiota of livestock rations containing different levels ofAIMS microbiology · 2025Article
- Interactions between rumen epithelium-associated microbiota and host immunological and metabolic adaptations in response to different milk replacer feeding intensities in dairy calves.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024Article
- The Rumen Microbiome Composition of Raramuri Criollo and European Cattle in an Extensive System.Microorganisms · 2024Article
- Effects of 5-Aminolevulinic Acid Supplementation on Gas Production, Fermentation Characteristics, and Bacterial Community Profiles In Vitro.Microorganisms · 2024Article
- Fetal Programming Influence on Microbiome Diversity and Ruminal and Cecal Epithelium in Beef Cattle.Animals : an open access journal from MDPI · 2024Article
- Repeated inoculation with rumen fluid accelerates the rumen bacterial transition with no benefit on production performance in postpartum Holstein dairy cows.Journal of animal science and biotechnology · 2024Article
- - Invited Review - Understanding the functionality of the rumen microbiota: searching for better opportunities for rumen microbial manipulation.Animal bioscience · 2024Article
- Survey of the fecal microbiota of indigenous small ruminants living in different areas of Guizhou.Frontiers in microbiology · 2024Article
- Successional action of Bacteroidota and Firmicutes in decomposing straw polymers in a paddy soil.Environmental microbiome · 2023Article
- Article
- Application of different proportions of sweet sorghum silage as a substitute for corn silage in dairy cows.Food science & nutrition · 2023Article
- The Impact of Mineral and Energy Supplementation and Phytogenic Compounds on Rumen Microbial Diversity and Nitrogen Utilization in Grazing Beef Cattle.Microorganisms · 2023Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
16 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ruminants have co-evolved with their gastrointestinal microbial communities that digest plant materials to provide energy for the host. Some arctic and boreal ruminants have already shown to be vulnerable to dietary shifts caused by changing climate, yet we know little about the metabolic capacity of the ruminant microbiome in these animals. Here, we use meta-omics approaches to sample rumen fluid microbial communities from Alaskan moose foraging along a seasonal lignocellulose gradient. Winter diets with increased hemicellulose and lignin strongly enriched for BS11, a Bacteroidetes family lacking cultivated or genomically sampled representatives. We show that BS11 are cosmopolitan host-associated bacteria prevalent in gastrointestinal tracts of ruminants and other mammals. Metagenomic reconstruction yielded the first four BS11 genomes; phylogenetically resolving two genera within this previously taxonomically undefined family. Genome-enabled metabolic analyses uncovered multiple pathways for fermenting hemicellulose monomeric sugars to short-chain fatty acids (SCFA), metabolites vital for ruminant energy. Active hemicellulosic sugar fermentation and SCFA production was validated by shotgun proteomics and rumen metabolites, illuminating the role BS11 have in carbon transformations within the rumen. Our results also highlight the currently unknown metabolic potential residing in the rumen that may be vital for sustaining host energy in response to a changing vegetative environment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.