Evidence map›Paper›PMID 27958700›Full record

ArticleAnalytical chemistry2017

Tandem Mass Spectrometry in Combination with Product Ion Mobility for the Identification of Phospholipids.

Karin A Zemski Berry, Robert M Barkley, Joseph J Berry, Joseph A Hankin, Emmy Hoyes, Jeffery M Brown, Robert C Murphy

Abstract read
In one paragraph

Article in Analytical chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Investigation into Drug-Induced Liver Damage Using Multimodal Mass Spectrometry Imaging.Journal of the American Society for Mass Spectrometry · 2025
    Article
  2. Identification and Imaging of Prostaglandin Isomers Utilizing MSJournal of the American Society for Mass Spectrometry · 2023
    Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karin A Zemski BerryDepartment of Pharmacology, University of Colorado Denver , Mail Stop 8303, 12801 E. 17th Avenue, Aurora, Colorado 80045, United States.ORCID 0000-0002-7089-691X
Robert M BarkleyDepartment of Pharmacology, University of Colorado Denver , Mail Stop 8303, 12801 E. 17th Avenue, Aurora, Colorado 80045, United States.ORCID 0000-0003-4711-6361
Joseph J BerryNational Renewable Energy Laboratory , 15013 Denver W Pkwy, Golden, Colorado 80401, United States.
Joseph A HankinDepartment of Pharmacology, University of Colorado Denver , Mail Stop 8303, 12801 E. 17th Avenue, Aurora, Colorado 80045, United States.
Emmy HoyesWaters Corporation, Altrincham Road, Wilmslow SK9 4AX, United Kingdom.
Jeffery M BrownWaters Corporation, Altrincham Road, Wilmslow SK9 4AX, United Kingdom.
Robert C MurphyDepartment of Pharmacology, University of Colorado Denver , Mail Stop 8303, 12801 E. 17th Avenue, Aurora, Colorado 80045, United States.ORCID 0000-0002-9430-6515

Funding

High Throughput Lipidomics Analysis by MALDI/Ion Mobility Mass SpectrometryR01ES022172 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI MURPHY, ROBERT CARL · 2012 to 2016
$1.9M
NIEHS NIH HHS R01 ES022172
6 · The paper itself

Abstract

Concerted tandem and traveling wave ion mobility mass spectrometry (CTS analysis) is a unique method that results in a four-dimensional data set including nominal precursor ion mass, product ion mobility, accurate mass of product ion, and ion abundance. This nontargeted lipidomics CTS approach was applied in both positive- and negative-ion mode to phospholipids present in human serum, and the data set was used to evaluate the value of product ion mobility in identifying lipids in a complex mixture. It was determined that the combination of diagnostic product ions and unique collisional cross-section values of product ions is a powerful tool in the structural identification of lipids in a complex biological sample.

Indexed as

HumansMass SpectrometryMolecular StructurePhospholipidsTandem Mass SpectrometryPhospholipids

Identifiers

PMID27958700
PMCPMC5250582

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.