Trial reportScientific reports2016
Selective perturbation of cognitive conflict in the human brain-A combined fMRI and rTMS study.
Trial report in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- Low-Frequency TMS Results in Condition-Related Dynamic Activation Changes of Stimulated and Contralateral Inferior Parietal Lobule.Frontiers in human neuroscience · 2021Article
- The neurocognitive underpinnings of the Simon effect: An integrative review of current research.Cognitive, affective & behavioral neuroscience · 2020Review
- Parsing the Flanker task to reveal behavioral and oscillatory correlates of unattended conflict interference.Scientific reports · 2019Article
- The effect of feature-based attention on flanker interference processing: An fMRI-constrained source analysis.Scientific reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated if single and double conflicts are processed separately in different brain regions and if they are differentially vulnerable to TMS perturbation. Fifteen human volunteers performed a single (Flanker or Simon) conflict task or a double (Flanker and Simon) conflict task in a combined functional Magnetic Resonance Imaging (fMRI) and Transcranial Magnetic Stimulation (TMS) study. The fMRI approach aimed at localizing brain regions involved in interference resolution induced by single Flanker (stimulus-stimulus, S-S) and Simon (stimulus-response, S-R) conflicts as well as regions involved in the double conflict condition. The data revealed a distinct activation in the right intraparietal sulcus (IPS) for Flanker interference and in the right middle frontal gyrus (MFG) for the double interference condition. The causal functional role of these brain regions was then examined in the same volunteers by using offline TMS over right IPS and right MFG. TMS perturbation of the right IPS increased the Flanker effect, but had no effect in the Simon or double conflict condition. In contrast, perturbation of the right MFG had no effect on any of the conflict types. These findings suggest a causal role of the right IPS in the processing of the single conflict of Flanker (stimulus-stimulus) interference.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.