Evidence map›Paper›PMID 27957699›Full record

ArticleObesity surgery2017

Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: a Joint Statement by International Diabetes Organizations.

Francesco Rubino, David M Nathan, Robert H Eckel, Philip R Schauer, K George M M Alberti, Paul Z Zimmet, Stefano Del Prato, Linong Ji, Shaukat M Sadikot, William H Herman and 5 more

Registry-linked trialAbstract readConsensus Statement
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06374368 (Jejuno-Ileal and Jejuno-Colic Diversion as a New Bariatric Method in the Treatment of Diabetes and Obesity), which is not on this map. Cited by 70 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 5 pooled it
19.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06374368 narecruitingnot on this mapstarted 2019, after this paper: background citation

Jejuno-Ileal and Jejuno-Colic Diversion as a New Bariatric Method in the Treatment of Diabetes and Obesity: Study Protocol for a Prospective Randomised Clinical Trial

TypeinterventionalSponsorUniversity of OstravaRan2019 to 2028Enrolled80ConditionsObesity, Type2 DiabetesArmsjejuno-ileal diversion, jejuno-colic diversion
3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 5 syntheses or guidelines pooled it, 185 citations in OpenAlex.

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  10. Adjustable gastric band surgery or medical management in patients with type 2 diabetes and obesity: three-year results of a randomized trial.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019
    Trial
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  12. Article
  13. [Obesity and type 2 diabetes mellitus (Update 2026)].Wiener klinische Wochenschrift · 2026
    Review
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 6 countries.

Francesco RubinoKing's College London, London, UK. francesco.rubino@kcl.ac.uk.
David M NathanHarvard Medical School, Boston, MA, USA.
Robert H EckelUniversity of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Philip R SchauerCleveland Clinic, Cleveland, OH, USA.
K George M M AlbertiImperial College London, London, UK.
Paul Z ZimmetMonash University, Melbourne, Victoria, Australia.
Stefano Del PratoUniversity of Pisa, Pisa, Italy.
Linong JiPeking University, Beijing, China.
Shaukat M SadikotDiabetes India, Mumbai, India.
William H HermanUniversity of Michigan, Ann Arbor, MI, USA.
Stephanie A AmielKing's College London, London, UK.
Lee M KaplanHarvard Medical School, Boston, MA, USA.
Gaspar Taroncher-Oldenburg, Philadelphia, PA, USA.
David E CummingsUniversity of Washington, Seattle, WA, USA. davidec@u.washington.edu.
Delegates of the 2nd Diabetes Surgery Summit
Harvard University · USCleveland Clinic · USKing's College London · GBUniversity of Pisa · ITUniversity of Washington · USImperial College London · GBPeking University · CNUniversity of Michigan · US

Funding

Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joyce Lee · 2010 to 2026
$20.3M
6 · The paper itself

Abstract

backgroundDespite growing evidence that bariatric/metabolic surgery powerfully improves type 2 diabetes (T2D), existing diabetes treatment algorithms do not include surgical options.

aimThe 2nd Diabetes Surgery Summit (DSS-II), an international consensus conference, was convened in collaboration with leading diabetes organizations to develop global guidelines to inform clinicians and policymakers about benefits and limitations of metabolic surgery for T2D.

methodsA multidisciplinary group of 48 international clinicians/scholars (75% nonsurgeons), including representatives of leading diabetes organizations, participated in DSS-II. After evidence appraisal (MEDLINE [1 January 2005-30 September 2015]), three rounds of Delphi-like questionnaires were used to measure consensus for 32 data-based conclusions. These drafts were presented at the combined DSS-II and 3rd World Congress on Interventional Therapies for Type 2 Diabetes (London, U.K., 28-30 September 2015), where they were open to public comment by other professionals and amended face-to-face by the Expert Committee.

resultsGiven its role in metabolic regulation, the gastrointestinal tract constitutes a meaningful target to manage T2D. Numerous randomized clinical trials, albeit mostly short/midterm, demonstrate that metabolic surgery achieves excellent glycemic control and reduces cardiovascular risk factors. On the basis of such evidence, metabolic surgery should be recommended to treat T2D in patients with class III obesity (BMI ≥40 kg/m

conclusionsAlthough additional studies are needed to further demonstrate long-term benefits, there is sufficient clinical and mechanistic evidence to support inclusion of metabolic surgery among antidiabetes interventions for people with T2D and obesity. To date, the DSS-II guidelines have been formally endorsed by 45 worldwide medical and scientific societies. Health care regulators should introduce appropriate reimbursement policies.

Indexed as

AlgorithmsBariatric SurgeryDiabetes Mellitus, Type 2Disease ManagementHumansRisk Factorsᅟ

Identifiers

PMID27957699
OpenAlexW2564833184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.