ArticleSleep & breathing = Schlaf & Atmung2017
The association between continuous positive airway pressure therapy and liver disease development in obstructive sleep apnea/hypopnea syndrome patients: a nationwide population-based cohort study in Taiwan.
Article in Sleep & breathing = Schlaf & Atmung, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Association between obstructive sleep apnea and non-alcoholic fatty liver disease: a systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2018Pooled it
- Management of non-alcoholic fatty liver disease patients with sleep apnea syndrome.World journal of gastroenterology · 2022Review
- Impact of continuous positive airway pressure therapy for nonalcoholic fatty liver disease in patients with obstructive sleep apnea.World journal of clinical cases · 2021Article
- Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: new trends and role of ultrasonography.Journal of medical ultrasonics (2001) · 2020Review
- Sleep disorder in patients with chronic liver disease: a narrative review.Journal of thoracic disease · 2020Review
- Stimulants associated with reduced risk of hospitalization for motor vehicle accident injury in patients with obstructive sleep apnea-a nationwide cohort study.BMC pulmonary medicine · 2020Article
- NAFLD and Extra-Hepatic Comorbidities: Current Evidence on a Multi-Organ Metabolic Syndrome.International journal of environmental research and public health · 2019Review
- Obstructive Sleep Apnea and the Liver.Clinics in liver disease · 2019Review
- The association between glycometabolism and nonalcoholic fatty liver disease in patients with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2019Article
- Obstructive Sleep Apnea in Children and Adolescents and the Risk of Major Adverse Cardiovascular Events: A Nationwide Cohort Study in Taiwan.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
- Effect of CPAP therapy on liver disease in patients with OSA: a review.Sleep & breathing = Schlaf & Atmung · 2018Review
- Sleep apnea, metabolic disease, and the cutting edge of therapy.Metabolism: clinical and experimental · 2018Review
- A Case of Concomitant Obstructive Sleep Apnea and Non-Alcoholic Steatohepatitis Treated With CPAP Therapy.Gastroenterology research · 2018Article
- Decreased expression of hepatic cytochrome P450 1A2 (CYP1A2) in a chronic intermittent hypoxia mouse model.Journal of thoracic disease · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeStudies on the association between continuous positive airway pressure (CPAP) treatment and liver diseases such as non-alcoholic fatty liver disease (NAFLD) and cirrhosis in patients with obstructive sleep apnea/hypopnea syndrome (OSAHS) are limited. To the best of our knowledge, none exists that makes use of a national database in an Asian population. This study aims to evaluate the effects of CPAP treatment on patients with these two disorders in a retrospective, population-based study in Taiwan.
methodsUsing the Taiwan National Health Insurance claims database, this study collected the data of OSAHS patients diagnosed between 2000 and 2008 and divided them into CPAP treatment and non-CPAP treatment groups. All subjects were followed up until 2010. Liver disease incidence and risk were calculated.
resultsThe CPAP group had a lower cumulative incidence rate of developing liver disease than the non-CPAP group within the observation periods (p < 0.001). After adjusting for age, gender, urbanization level, and comorbidities, the CPAP treatment group showed a lower risk of developing liver disease compared with the non-CPAP treatment group (sub-aHR of 0.66 (95% CI 0.55-0.80), p < 0.001).
conclusionsOur observations suggest that CPAP treatment may play an important role to delay the progression of liver disease in OSAHS patients and decreases the incidence of liver disease among OSAHS patients. Thus, CPAP therapy may be a feasible way to decrease the risk of liver disease among patients with OSAHS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.