Evidence map›Paper›PMID 27957683›Full record

ArticleMolecular neurobiology2018

Heterogeneity of Brain Ribosomal Genes Expression Following Positive Fighting Experience in Male Mice as Revealed by RNA-Seq.

Dmitry A Smagin, Irina L Kovalenko, Anna G Galyamina, Yuriy L Orlov, Vladimir N Babenko, Natalia N Kudryavtseva

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  3. Recent Trends in Cancer Genomics and Bioinformatics Tools Development.International journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dmitry A SmaginInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, pr. Ac. Lavrentyeva, 10, Novosibirsk, 630090, Russia.
Irina L KovalenkoInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, pr. Ac. Lavrentyeva, 10, Novosibirsk, 630090, Russia.
Anna G GalyaminaInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, pr. Ac. Lavrentyeva, 10, Novosibirsk, 630090, Russia.
Yuriy L OrlovInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, pr. Ac. Lavrentyeva, 10, Novosibirsk, 630090, Russia.
Vladimir N BabenkoInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, pr. Ac. Lavrentyeva, 10, Novosibirsk, 630090, Russia. bob@bionet.nsc.ru.
Natalia N KudryavtsevaInstitute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, pr. Ac. Lavrentyeva, 10, Novosibirsk, 630090, Russia. n.n.kudryavtseva@gmail.com.
Institute of Cytology and Genetics · RUNovosibirsk State University · RU

Funding

Russian Science Foundation 14-14-00269Russian Science Foundation 14-15-00063
6 · The paper itself

Abstract

Repeated positive fighting experience in daily agonistic interactions is accompanied by changes of brain neurotransmitter activity and genes' expression in male mice. This paper is focused on the analysis of ribosomal genes expression data as revealed by whole-transcriptome analysis (RNA-Seq) in five brain regions of male mice with long repeated experience of aggression accompanied by wins (winners). Downregulation of most Rps, Rpl, Mrps, and Mrpl genes was found in the midbrain raphe nuclei and striatum and upregulation-in the hippocampus and hypothalamus of the winners. There were no changes in ribosomal gene expression in the ventral tegmental area. The data allow considering the alteration in ribosomal gene expression as an animal model of ribosomal dysfunction developed under positive fighting experience in male mice.

Indexed as

AggressionAnimalsBrainGene ExpressionMaleMiceMice, Inbred C57BLRibosomal ProteinsSequence Analysis, RNARibosomal ProteinsMiceMitochondrial pathologyMrpl genesMrps genesPositive fighting experienceRepeated aggressionRibosomopathiesRpl genesRps genes

Identifiers

PMID27957683
OpenAlexW2563569911

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.