Evidence map›Paper›PMID 27957667›Full record

ReviewJournal of genetic counseling2017

Clinical Cancer Genetics Disparities among Latinos.

Marcia Cruz-Correa, Julyann Pérez-Mayoral, Julie Dutil, Miguel Echenique, Rafael Mosquera, Keila Rivera-Román, Sharee Umpierre, Segundo Rodriguez-Quilichini, Maria Gonzalez-Pons, Myrta I Olivera and 2 more

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Journal of genetic counseling, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06476938 (Testing the Efficacy of an eHealth Decision Support Tool to Help Latinx Cancer Patients Make Informed Decisions About Tumor Genomic Testing), which is not on this map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06476938 narecruitingnot on this mapstarted 2025, after this paper: background citation

Testing the Efficacy of an eHealth Decision Support Tool to Help Latinx Cancer Patients Make Informed Decisions About Tumor Genomic Testing

TypeinterventionalSponsorFox Chase Cancer CenterRan2025 to 2027Enrolled232ConditionsCancerArmsGene PilotLX
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Marcia Cruz-CorreaDivision of Cancer Biology, University of Puerto Rico Comprehensive Cancer Center, PMB711 Ave. De Diego 89 Ste. 105, San Juan, PR, 00927-6346, USA. marcia.cruz1@upr.edu.
Julyann Pérez-MayoralDivision of Cancer Biology, University of Puerto Rico Comprehensive Cancer Center, PMB711 Ave. De Diego 89 Ste. 105, San Juan, PR, 00927-6346, USA.
Julie DutilPonce Research Institute, Ponce Health Sciences University, Ponce, PR, USA.
Miguel EcheniqueCancer Center, Auxilio Mutuo Hospital, San Juan, PR, USA.
Rafael MosqueraPuerto Rico Gastroenterology Association, San Juan, PR, USA.
Keila Rivera-RománDepartment of Pediatrics, University of Puerto Rico School of Medicine, San Juan, PR, USA.
Sharee UmpierreDivision of Cancer Biology, University of Puerto Rico Comprehensive Cancer Center, PMB711 Ave. De Diego 89 Ste. 105, San Juan, PR, 00927-6346, USA.
Segundo Rodriguez-QuilichiniDivision of Cancer Biology, University of Puerto Rico Comprehensive Cancer Center, PMB711 Ave. De Diego 89 Ste. 105, San Juan, PR, 00927-6346, USA.
Maria Gonzalez-PonsDivision of Cancer Biology, University of Puerto Rico Comprehensive Cancer Center, PMB711 Ave. De Diego 89 Ste. 105, San Juan, PR, 00927-6346, USA.
Myrta I OliveraDivision of Cancer Biology, University of Puerto Rico Comprehensive Cancer Center, PMB711 Ave. De Diego 89 Ste. 105, San Juan, PR, 00927-6346, USA.
Sherly PardoDepartment of Pathology, University of Puerto Rico School of Medicine, San Juan, PR, USA.
Puerto Rico Clinical Cancer Genetics Consortia
University of Puerto Rico System · PRAuxilio Mutuo Hospital · PRClinical Research Puerto Rico · PRPonce Health Sciences University · PR

Funding

UPR/MDACC Partnership for Excellence in Cancer Research(Parent Grant U54 CA096297)U54CA096297 · NCI · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Ilka C Rios · 2002 to 2026
$36.9M
UPR/MDACC Partnership for Excellence in Cancer Research (Luis Segarra supplement)U54CA096300 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Larkin Strong · 2002 to 2026
$23.8M
TECHNOLOGIES AND RESOURCES FOR CORE LABORATORIESU54MD007587 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI LUCIANO, CARLOS A., WOJNA, VALERIE · 2012 to 2018
$23.2M
Using MC1R genotype to impact skin cancer risk behaviors in Hispanics/LatinosU54CA163068 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI KENNETH Lynn WRIGHT · 2012 to 2026
$23.1M
Using MC1R genotype to impact skin cancer risk behaviors in Hispanics/LatinosU54CA163071 · NCI · PONCE SCHOOL OF MEDICINE · PI Luisa Morales-Torres · 2012 to 2026
$23.0M
FUNCTIONAL ANALYSIS OF BRCA1 MUTANTSR01CA092309 · NCI · STRANG CANCER PREVENTION CENTER · PI MONTEIRO, ALVARO N · 2002 to 2006
$1.3M
Familial Colorectal Cancer Registry in Puerto Rico: A Feasibility StudyR03CA130034 · NCI · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI CRUZ-CORREA, MARCIA ROXANA · 2007 to 2009
$188k
NCI NIH HHS R01 CA092309NCI NIH HHS R03 CA130034NCI NIH HHS U54 CA096297NCI NIH HHS U54 CA096300NCI NIH HHS U54 CA163068NCI NIH HHS U54 CA163071NIMHD NIH HHS U54 MD007587
6 · The paper itself

Abstract

The three major hereditary cancer syndromes in Latinos (Hereditary Breast and Ovarian Cancer, Familial Adenomatous Polyposis and Lynch Syndrome) have been shown to exhibit geographic disparities by country of origin suggesting admixture-based disparities. A solid infrastructure of clinical genetics geared towards diagnosis and prevention could aid in reducing the mortality of these cancer syndromes in Latinos. Currently, clinical cancer genetic services in Latin America are scarce. Moreover, limited studies have investigated the mutational spectrum of these cancer syndromes in Latinos resulting in gaps in personalized medicine affecting diagnosis, treatment and prevention. The following commentary discusses available genotype and clinical information on hereditary cancer in Latinos and highlights the limited access for cancer genetic services in Latin America including barriers to genetic testing and alternatives for providing better access to genetic services. In this review, we discuss the status of clinical genetic cancer services for both US Latinos and those Latinos living in Latin America.

Indexed as

Early Detection of CancerFemaleGenetic TestingHealthcare DisparitiesHispanic or LatinoHumansLatin AmericaMaleMutationNeoplastic Syndromes, HereditaryUnited StatesGenetic counselingGenetic testingHealth disparitiesHereditary cancerHispanics

Identifiers

PMID27957667
PMCPMC5418082
OpenAlexW2564383130

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.