SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2017
Topical interventions to prevent acute radiation dermatitis in head and neck cancer patients: a systematic review.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 84 citations in OpenAlex.
- Potential Single Nucleotide Polymorphisms markers for radiation dermatitis in head and neck cancer patients: a meta-analysis.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024Pooled it
- Topical non-steroidal agents for the prevention of radiation dermatitis: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Pooled it
- Natural and miscellaneous agents for the prevention of acute radiation dermatitis: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Pooled it
- Topical Treatment of Oral Mucositis in Cancer Patients: A Systematic Review of Randomized Clinical Trials.Asian Pacific journal of cancer prevention : APJCP · 2020Pooled it
- Compound staphylococcal lysostaphin for oral mucositis prophylaxis in hematopoietic stem cell transplantation recipients: a non-inferiority randomized trial.British journal of cancer · 2026Trial
- A novel, multi-active emollient for the prevention of acute radiation dermatitis in breast cancer patients: a randomized clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Trial
- What is the appropriate skin cleaning method for nasopharyngeal cancer radiotherapy patients? A randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Trial
- Mepitel Film is superior to Biafine cream in managing acute radiation-induced skin reactions in head and neck cancer patients: a randomised intra-patient controlled clinical trial.Journal of medical radiation sciences · 2020Trial
- Utility of topical agents for radiation dermatitis and pain: a randomized clinical trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Trial
- Prophylactic NS-21 maintains the skin moisture but does not reduce the severity of radiation dermatitis in patients with head and neck cancer: a randomized control trial.Radiation oncology (London, England) · 2019Trial
- The effect of Mepitel Film on acute radiation-induced skin reactions in head and neck cancer patients: a feasibility study.The British journal of radiology · 2018Trial
- Evidence summary on non-pharmacological interventions of the radiation dermatitis in patients with head and neck cancer.Asia-Pacific journal of oncology nursing · 2026Review
- Management of Radiodermatitis in Patients With Head and Neck Cancer Undergoing Radiotherapy: A Scoping Review.Health care science · 2026Review
- Combination of Danggui Buxue Tang and concurrent chemoradiotherapy improves treatment outcomes by strengthening B cell immunity in patients with nasopharyngeal carcinoma-a double-blind, randomized trial.Translational cancer research · 2025Article
- Feature-Based vs. Deep-Learning Fusion Methods for the In Vivo Detection of Radiation Dermatitis Using Optical Coherence Tomography, a Feasibility Study.Journal of imaging informatics in medicine · 2025Article
- Article
- Prevention and management of radiodermatitis in patients with brachytherapy for gynecologic neoplasms summary of the evidence.Frontiers in oncology · 2025Review
- Exploring Black Soybean Extract Cream for Inflammatory Dermatitis-Toward Radiation Dermatitis Relief.International journal of molecular sciences · 2024Article
- Keratin-based topical cream for radiation dermatitis during head and neck radiotherapy: a randomised, open-label pilot study.Journal of radiotherapy in practice · 2024Article
- Chinese clinical practice guidelines for the prevention and treatment of radiation-induced dermatitis.Precision radiation oncology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of the study is to evaluate the effects of pharmacological and non-pharmacological topical controls in the prevention of radiation dermatitis.
methodsRelevant clinical trials were identified through electronic searching databases CINAHL, CENTRAL, LILACS, PubMed, Scopus, and Web of Science. Handsearching and gray literature searches were also performed to find additional references. Primary outcomes of interest were the development of radiation dermatitis and the time of occurrence of radiation dermatitis.
resultsThirteen randomized clinical trials were included in this review. The trials were published in Chinese, English, or French, from 1980 to 2015. Pharmacological interventions used in the trials were trolamine, aloe vera, allantoin, Lianbai liquid, sucralfate, Na-sucrose octasulfate, olive oil, hialuronic acid, and dexpanthenol. Non-pharmacological topical controls were usual care/institution routine, aqueous cream, mild soap, water thermal gel, placebo, and no intervention.
conclusionsThere was no strong evidence that indicates differences between topical pharmacological interventions or non-pharmacological topical controls in the prevention of acute radiation dermatitis among patients with head and neck cancer undergoing radiotherapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.