ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2017
Evaluation of the BioFire FilmArray® GastrointestinalPanel in a Midwestern Academic Hospital.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 62 citations in OpenAlex.
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- Epidemiology of Single-Etiology Non-Shiga Toxin-ProducingFood protection trends · 2026Article
- Detection and assessment of fecal carriage of gastrointestinal pathogens in healthy community adults: a year-long study.BMC infectious diseases · 2026Article
- Patterns of gastrointestinal pathogen co-detection in pediatric stool samples identified by rapid multiplex PCR.Epidemiology and infection · 2026Article
- Associations Between BioFire FilmArray Gastrointestinal Panel Results and Clinical Outcomes in Infectious Gastroenteritis.Diagnostics (Basel, Switzerland) · 2025Article
- Multiplex Polymerase Chain Reaction Panels for Gastrointestinal Infections: Current Evidence, Regulatory Hurdles, and the Way Forward.Open forum infectious diseases · 2025Article
- Bacteremic vs NonbacteremicOpen forum infectious diseases · 2025Article
- Review
- Multicenter evaluation of the QIAstat-Dx Gastrointestinal Panel 2, a multiplex PCR platform for the diagnosis of acute gastroenteritis.Journal of clinical microbiology · 2025Article
- Acute infectious gastroenteritis in childhood: the role of rapid multiplex molecular syndromic panels in diagnosis and clinical management.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025Review
- Clinical Performance of the LiquidArrayDiagnostics (Basel, Switzerland) · 2024Article
- Syndromic Gastrointestinal Panel Diagnostic Tests Have Changed our Understanding of the Epidemiology ofOpen forum infectious diseases · 2024Article
- Postpandemic Effects of COVID-19 Shelter-in-Place Orders on the Gastrointestinal Pathogen Landscape.Journal of clinical microbiology · 2023Article
- The Impact of a Positive BiofireDiagnostics (Basel, Switzerland) · 2023Article
- Detection of Foodborne Pathogens in Acute Gastroenteritis Patient's Stool Samples Using the BioFireMicroorganisms · 2022Article
- Changing Diagnostic Testing Practices for Foodborne Pathogens, Foodborne Diseases Active Surveillance Network, 2012-2019.Open forum infectious diseases · 2022Article
- Review
- Impact of COVID-19 Shelter-in-Place Order on Transmission of Gastrointestinal Pathogens in Northern California.Journal of clinical microbiology · 2021Article
- Evidence of False Positivity forOpen forum infectious diseases · 2021Article
- Real-time gastrointestinal infection surveillance through a cloud-based network of clinical laboratories.PloS one · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The BioFire FilmArray® Gastrointestinal Panel (GIP) was implemented to replace traditional stool culture and enzyme immunoassay (EIA) testing for stool pathogens. The purpose of this study was to evaluate the detection rate, incidence of coinfection, and culture recovery rate of gastrointestinal (GI) pathogens detected by the GIP over a 1-year period. A total of 2257 stools collected from January to December 2015 were tested using the GIP. Clostridium difficile colonization was also evaluated by an antigen/toxin EIA and confirmatory polymerase chain reaction (PCR). The GIP detected one pathogen in 911 (40.4%) specimens. Coinfections were detected in 176 (7.8%) of these specimens. The most frequently detected pathogens were C. difficile (15.2%), norovirus (8.9%), enteropathogenic Escherichia coli (7.1%), enteroaggregative E. coli (3.4%), Campylobacter spp. (2.3%), and sapovirus (2.0%). Each of the remaining GIP targets had a detection rate of ≤1.6%. The recovery of bacteria for public health investigations varied, with rates as high as 77% for Salmonella to as low as 30% for Yersinia enterocolitica. Of stools positive for C. difficile on the GIP that were tested by EIA, only 42.7% (88/206) were found to be producing detectable toxin. Overall, the implementation of the GIP resulted in high detection rates of GI pathogens, including the frequent detection of coinfections. This is a promising test to streamline the testing of agents causing infectious gastroenteritis from multiple tests down to a single order with limited hands-on time. Ongoing studies will need to assess the impact that the GIP has on downstream patient care and public health practices.
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