Evidence map›Paper›PMID 27957539›Full record

ArticleScience advances2016

Dramatic influence of patchy attractions on short-time protein diffusion under crowded conditions.

Saskia Bucciarelli, Jin Suk Myung, Bela Farago, Shibananda Das, Gerard A Vliegenthart, Olaf Holderer, Roland G Winkler, Peter Schurtenberger, Gerhard Gompper, Anna Stradner

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Lipoprotein diffusion in dense yolk plasma is governed by softness, hydrodynamics, and caging: Insights from MHz-XPCS.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  15. Whole-Cell Models and Simulations in Molecular Detail.Annual review of cell and developmental biology · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Saskia BucciarelliDivision of Physical Chemistry, Department of Chemistry, Lund University, Naturvetarvägen 16, SE-221 00 Lund, Sweden.ORCID 0000-0001-7612-223X
Jin Suk MyungDivision of Physical Chemistry, Department of Chemistry, Lund University, Naturvetarvägen 16, SE-221 00 Lund, Sweden.; Theoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, D-52425 Jülich, Germany.
Bela FaragoInstitut Laue-Langevin (ILL), F-38042 Grenoble Cedex 9, France.
Shibananda DasTheoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, D-52425 Jülich, Germany.ORCID 0000-0001-7694-0654
Gerard A VliegenthartTheoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, D-52425 Jülich, Germany.ORCID 0000-0003-2459-8652
Olaf HoldererJülich Centre for Neutron Science (JCNS) at Heinz Maier-Leibnitz Zentrum (MLZ), Forschungszentrum Jülich GmbH, Lichtenbergstr. 1, D-85748 Garching, Germany.ORCID 0000-0001-6746-7965
Roland G WinklerTheoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, D-52425 Jülich, Germany.ORCID 0000-0002-7513-0796
Peter SchurtenbergerDivision of Physical Chemistry, Department of Chemistry, Lund University, Naturvetarvägen 16, SE-221 00 Lund, Sweden.ORCID 0000-0002-2790-8831
Gerhard GompperTheoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, D-52425 Jülich, Germany.ORCID 0000-0002-8904-0986
Anna StradnerDivision of Physical Chemistry, Department of Chemistry, Lund University, Naturvetarvägen 16, SE-221 00 Lund, Sweden.; Department of Chemistry, University of Fribourg, Chemin du Musée 9, CH-1700 Fribourg, Switzerland.ORCID 0000-0003-3310-3412
Forschungszentrum Jülich · DELund University · SEInstitut Laue-Langevin · FRUniversity of Fribourg · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the dense and crowded environment of the cell cytoplasm, an individual protein feels the presence of and interacts with all surrounding proteins. While we expect this to strongly influence the short-time diffusion coefficient

Indexed as

DiffusionAnimalsCattleComputer SimulationCrystallinsCytoplasmCrystallinsanisotropic interactionscomputer simulationshydrodynamic interactionsmultiparticle collision dynamicsneutron spin echo techniqueProtein crowdingprotein diffusionprotein-protein interactionsshort-time dynamics

Identifiers

PMID27957539
PMCPMC5142800
OpenAlexW2560582775

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.