Evidence map›Paper›PMID 27957519›Full record

ArticleEuropean journal of radiology open2016

Low dose chest CT protocol (50 mAs) as a routine protocol for comprehensive assessment of intrathoracic abnormality.

Takeshi Kubo, Yoshiharu Ohno, Mizuki Nishino, Pei-Jan Lin, Shiva Gautam, Hans-Ulrich Kauczor, Hiroto Hatabu, iLEAD study group

Open access · goldAbstract read
In one paragraph

Article in European journal of radiology open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. The radiological diagnosis of bronchiectasis: what's in a name?European respiratory review : an official journal of the European Respiratory Society · 2020
    Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 3 countries.

Takeshi KuboDepartment of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
Yoshiharu OhnoDepartment of Radiology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Mizuki NishinoDepartment of Radiology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, United States.
Pei-Jan LinDepartment of Radiology, Virginia Commonwealth University Medical Center, 1101 East Marshall Street, Room 4-052, Richmond, VA 23298 United States.
Shiva GautamDepartments of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, United States.
Hans-Ulrich KauczorDiagnostic and Interventional Radiology, University Clinic Heidelberg, Im Neuenheimer Feld 110, D-69120 Heidelberg, Germany.
Hiroto HatabuDepartment of Radiology, Brigham and Women's Hospital, 75 Francis Street Boston, MA 02115, United States.
iLEAD study group
Beth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USDana-Farber Cancer Institute · USHeidelberg University · DEKobe University · JPKyoto University · JPVirginia Commonwealth University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the diagnostic capability of low-dose CT (50 mAs) in comparison to standard-dose CT (150 mAs). MATERIALS AND

methodsFifty-nine consecutive patients underwent two non-contrast chest CT scans with different current-time products (50 and 150 mAs at 120 kVp) on a 64-detector row CT scanner. Three board certified chest radiologists independently reviewed 118 series of 2 mm-thick images (2 series for each of 59 patients) in a random order. The readers assessed abnormal findings including emphysema, ground-glass opacity, reticular opacity, micronodules, bronchiectasis, honeycomb, nodules (>5 mm), aortic aneurysm, coronary artery calcification, pericardial and pleural effusion, pleural thickening, mediastinal tumor and lymph node enlargement. Five-point scale from 1 (definitely absent) to 5 (definitely present) was used to record the results. The rates of score agreement between two images were calculated. Deviation of one observer's score from other two observers was compared between low dose CT and standard dose CT.

resultsMean agreement rate of the lung parenchymal findings between low dose CT and standard dose CT images was 0.836 (range, 0.746-0.926). Mean agreement rates for mediastinal and pleural findings were 0.920 (range, 0.735-1.000). There was no statistically significant difference in the deviation of the observers' scores between low-dose CT and standard-dose CT.

conclusionLow dose CT protocol at 50 mAs can produce the screening results consistent with standard dose CT protocol (150 mAs), supporting routine use of low dose chest CT protocol.

Indexed as

Chest CTDiagnostic accuracyRadiation dose reduction

Identifiers

PMID27957519
PMCPMC5144113
OpenAlexW2343154622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.