Evidence map›Paper›PMID 27957429›Full record

ArticleBBA clinical2016

Relationship between level of HbA1C and breast cancer.

Fariba Jousheghany, Joshua Phelps, Tina Crook, Reza Hakkak

Abstract read
In one paragraph

Article in BBA clinical, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. HbABMC cancer · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
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  12. Article
  13. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fariba JousheghanyDepartments of Dietetics and Nutrition, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Joshua PhelpsDepartments of Dietetics and Nutrition, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Tina CrookDepartments of Dietetics and Nutrition, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA.
Reza HakkakDepartments of Dietetics and Nutrition, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA; Departments of Pediatrics, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR 72205, USA; Arkansas Children's Hospital Research Institute, 13 Children's Way., Little Rock, AR 72202, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes and cancer are public health issues worldwide; studies have shown that diabetes is related to increased breast cancer mortality. The purpose of this study was to examine associations between HbA1C and obesity with tumor stage and mortality among breast cancer patients.

methodsData for 82 patients with breast cancer (36-89 years of age, diagnosed /treated 1999-2009) were provided by the University of Arkansas for Medical Sciences (UAMS) Data Trust Warehouse. Survival time was estimated from start date of service to date of last follow-up or date of death. The Kaplan-Meier method provided analysis of survival curves for two groups of HbA1C (HbA1C < 6.5% vs HbA1C ≥ 6.5%) and two groups of BMI (BMI < 30 vs BMI ≥ 30 kg/m2); survival curves were compared using log-rank tests. Associations between HbA1C and BMI, and between HbA1C and tumor stage were determined by chi-square.

resultsThe relationship between tumor stages and HbA1C was not statistically significant (X

conclusionWhile there was a statistically significant association between HbA1C and obesity, there were no significant associations found with this analysis. However, there are clinically meaningful relationships based on observed trends. Future directions for research may involve exploring a larger sample of patients and the role of therapeutic regimens on blood sugar control and BMI of breast cancer patients and influence on cancer prognosis.

Indexed as

Breast cancerDiabetesHbA1CObesityTumor stage

Identifiers

PMID27957429
PMCPMC5144103

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.