Evidence map›Paper›PMID 27957327›Full record

ArticleImmunity, inflammation and disease2016

Altered expression of Butyrophilin (

Cristina Lebrero-Fernández, Ulf Alexander Wenzel, Paulina Akeus, Ying Wang, Hans Strid, Magnus Simrén, Bengt Gustavsson, Lars G Börjesson, Susanna L Cardell, Lena Öhman and 2 more

Open access · goldAbstract read
In one paragraph

Article in Immunity, inflammation and disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Cristina Lebrero-FernándezDepartment of Microbiology and Immunology Institute of Biomedicine University of Gothenburg Gothenburg Sweden.
Ulf Alexander WenzelDepartment of Microbiology and Immunology Institute of Biomedicine University of Gothenburg Gothenburg Sweden.
Paulina AkeusDepartment of Microbiology and Immunology Institute of Biomedicine University of Gothenburg Gothenburg Sweden.
Ying WangDepartment of Microbiology and Immunology Institute of Biomedicine University of Gothenburg Gothenburg Sweden.
Hans StridDepartment of Internal Medicine and Clinical Nutrition Institute of Medicine University of Gothenburg Gothenburg Sweden.
Magnus SimrénDepartment of Internal Medicine and Clinical NutritionInstitute of MedicineUniversity of GothenburgGothenburgSweden; Center for Functional GI and Motility DisordersUniversity of North CarolinaChapel HillNorth CarolinaUSA.
Bengt GustavssonDepartment of Surgery Institute of Clinical Sciences University of Gothenburg Gothenburg Sweden.
Lars G BörjessonDepartment of Surgery Institute of Clinical Sciences University of Gothenburg Gothenburg Sweden.
Susanna L CardellDepartment of Microbiology and Immunology Institute of Biomedicine University of Gothenburg Gothenburg Sweden.
Lena ÖhmanDepartment of Microbiology and ImmunologyInstitute of BiomedicineUniversity of GothenburgGothenburgSweden; Department of Internal Medicine and Clinical NutritionInstitute of MedicineUniversity of GothenburgGothenburgSweden; School of Health and EducationUniversity of SkövdeSkövdeSweden.
Marianne Quiding-JärbrinkDepartment of Microbiology and Immunology Institute of Biomedicine University of Gothenburg Gothenburg Sweden.
Anna Bas-ForsbergDepartment of Microbiology and Immunology Institute of Biomedicine University of Gothenburg Gothenburg Sweden.
University of Gothenburg · SEUniversity of Skövde · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several Butyrophilin (BTN) and Btn-like (BTNL) molecules control T lymphocyte responses, and are genetically associated with inflammatory disorders and cancer. In this study, we present a comprehensive expression analysis of human and murine

Indexed as

AnimalsButyrophilinsColitis, UlcerativeColonColonic NeoplasmsHumansInflammationIntestinal MucosaMiceMice, Inbred C57BLT-LymphocytesBtnl1 protein, mouseBTNL2 protein, humanButyrophilinsButyrophilin (Btn)‐like (Btnl)colon cancerimmune regulationintestinal inflammationirritable bowel syndrome (IBS)ulcerative colitis (UC)

Identifiers

PMID27957327
PMCPMC4879465
OpenAlexW2321483073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.