ArticleWorld journal of cardiology2016
Outcomes and long-term survival of coronary artery surgery: The controversial role of opium as risk marker.
Article in World journal of cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- The effects of opium on the cardiovascular system: a review of side effects, uses, and potential mechanisms.Substance abuse treatment, prevention, and policy · 2020Pooled it
- How Does Opium Dependency Affect the Myocardial Infarction Outcomes? :.Galen medical journal · 2025Article
- Predicting Factors Affecting Survival Rate in Patients Undergoing On-Pump Coronary Artery Bypass Graft Surgery Using Machine Learning Methods: A Systematic Review.Health science reports · 2025Review
- The effects of opium consumption on severity of disease on hospitalized COVID-19 patients in East of Iran, a prospective cohort study.Translational and clinical pharmacology · 2024Article
- Is high sensitive-troponin I a reliable biomarker for cardiac injury in methadone toxicity? A prospective cross-sectional study.BMC pharmacology & toxicology · 2022Article
- Clusters of the Risk Markers and the Pattern of Premature Coronary Heart Disease: An Application of the Latent Class Analysis.Frontiers in cardiovascular medicine · 2021Article
- The association between dietary quality indices and serum telomerase activity in patient candidates for CABG.Eating and weight disorders : EWD · 2020Observational
- Article
- Dietary acid load significantly predicts 10-years survival in patients underwent coronary artery bypass grafting (CABG) surgery.PloS one · 2019Article
- Coronary Artery Bypass Graft Surgery Outcomes Following 6.5 Years: A Nested Case-control Study.International journal of preventive medicine · 2017Article
- Opium and cardiovascular health: A devil or an angel?Indian heart journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo study survival in isolated coronary artery bypass graft (CABG) patients and to evaluate the impact of preoperative chronic opium consumption on long-term outcome.
methodsCohort of 566 isolated CABG patients as Tehran Heart Center cardiac output measurement was conducted. Daily evaluation until discharge as well as 4- and 12-mo and 6.5-year follow-up information for survival status were fulfilled for all patients. Long-term 6.5-year overall and opium-stratified survival, adjusted survival curves based on opium consumption as well as possible predictors of all-cause mortality using multiple cox regression were determined by statistical analysis.
resultsSix point five-year overall survival was 91.8%; 86.6% in opium consumers and 92.7% in non-opium consumers (
conclusionSimultaneous impact of smoking as a confounding variable in most of the patients prevents from definitive judgment on the role of opium as an independent contributing factor in worse long-term survival of CABG patients in addition to advanced age, low EF, diabetes mellitus and cerebrovascular accident. Meanwhile, our findings do not confirm any cardio protective role for opium to improve outcome in coronary patients with the history of smoking. Further studies are needed to clarify pure effect of opium and warrant the aforementioned findings.
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