Evidence map›Paper›PMID 27957244›Full record

ArticleWorld journal of hepatology2016

Neglected features of lifestyle: Their relevance in non-alcoholic fatty liver disease.

Francesca M Trovato, Giuseppe Fabio Martines, Daniela Brischetto, Guglielmo Trovato, Daniela Catalano

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of hepatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05618626 (Cardiovascular Diseases), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05618626 narecruitingnot on this mapstarted 2021, after this paper: background citation

Cardiovascular Diseases (CVD) and Nonalcoholic Fatty Liver Diseases (NAFLD) Among Gallstone and Cholecystectomy Patients and the Impact of a Novel Diet and Muscle Training Program

TypeinterventionalSponsorPontificia Universidad Catolica de ChileRan2021 to 2025Enrolled300ConditionsNon-Alcoholic Fatty Liver Disease, Gallstone DiseaseArmsPhysical exercise and dietary intervention for NAFLD
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. ESPEN guideline on clinical nutrition in liver disease.Clinical nutrition (Edinburgh, Scotland) · 2019
    Guideline
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Adherence to Mediterranean Diet: Any Association with NAFLD?Antioxidants (Basel, Switzerland) · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Francesca M TrovatoFrancesca M Trovato, Giuseppe Fabio Martines, Daniela Brischetto, Daniela Catalano, Department of Clinical and Experimental Medicine, Postgraduate School of Clinical Echography, the University of Catania, 95100 Catania, Italy.
Giuseppe Fabio MartinesFrancesca M Trovato, Giuseppe Fabio Martines, Daniela Brischetto, Daniela Catalano, Department of Clinical and Experimental Medicine, Postgraduate School of Clinical Echography, the University of Catania, 95100 Catania, Italy.
Daniela BrischettoFrancesca M Trovato, Giuseppe Fabio Martines, Daniela Brischetto, Daniela Catalano, Department of Clinical and Experimental Medicine, Postgraduate School of Clinical Echography, the University of Catania, 95100 Catania, Italy.
Guglielmo TrovatoFrancesca M Trovato, Giuseppe Fabio Martines, Daniela Brischetto, Daniela Catalano, Department of Clinical and Experimental Medicine, Postgraduate School of Clinical Echography, the University of Catania, 95100 Catania, Italy.
Daniela CatalanoFrancesca M Trovato, Giuseppe Fabio Martines, Daniela Brischetto, Daniela Catalano, Department of Clinical and Experimental Medicine, Postgraduate School of Clinical Echography, the University of Catania, 95100 Catania, Italy.
University of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigated in non-alcoholic-fatty-liver-disease (NAFLD), with ultrasound (US)-detected fatty liver, and in a group of non-alcoholic and otherwise healthy subjects, relationship of neglected features of lifestyle with NAFLD and obesity.

methodsFive hundred and thirty-two NAFLD and 667 non-NAFLD healthy subjects, age 21-60 years were studied. Severity of liver steatosis was assessed by US bright liver score. The adherence to mediterranean diet score (AMDS) was assessed on the basis of a 1-wk recall computerized questionnaire which included a detailed physical activity reports (Baecke questionnaire). The western dietary profile score, as a simplified paradigm of unhealthy diet, a questionnaire quantifying sun exposure score and a sleep habits questionnaires provided a further comprehensive lifestyle assessment.

resultsBody mass index (BMI), insulin resistance (HOMA), and triglycerides, poorer adherence to a mediterranean diet profile, sedentary habits, minor sun exposure and use of "western diet" foods are greater in NAFLD. Multiple linear regression analysis, weighted by years of age, displays BMI, HOMA and AMDS as the most powerful independent predictors of fatty liver severity; however, also the physical activity score, the western diet habit and the sun exposure score are acting inside the model with significant independent effects.

conclusionArticulated clinical intervention, according to our results, are justified in NAFLD and can be pursued addressing by focused intervention nutritional profile, physical exercise mainly in open-air subsets for enhancing sun exposure and healthier sleep duration and rhythm.

Indexed as

Clinical risk managementDietFatty liverHealth psychologyMalnutritionObesitySleepSun exposureUltrasound

Identifiers

PMID27957244
PMCPMC5124717
OpenAlexW2553321823

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.