Evidence map›Paper›PMID 27957016›Full record

ArticleGastroenterology research2011

Predictability of Gastric Intestinal Metaplasia by Mottled Patchy Erythema Seen on Endoscopy.

Naoyoshi Nagata, Takuro Shimbo, Junichi Akiyama, Ryo Nakashima, Hyung Hun Kim, Takeichi Yoshida, Kazufusa Hoshimoto, Naomi Uemura

Open access · hybridAbstract read
In one paragraph

Article in Gastroenterology research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
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  11. Image-enhanced endoscopy in upper GI tract: State-of-the-art review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. [Clinical Application of the Kyoto Classification of Gastritis].The Korean journal of helicobacter and upper gastrointestinal research · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Naoyoshi NagataDepartment of Gastroenterology and Hepatology, National Center for Global Health and Medicine (NCGM), Tokyo, Japan.
Takuro ShimboDepartment of Clinical Research and Informatics International Clinical Research Center Research Institute, NCGM, Tokyo, Japan.
Junichi AkiyamaDepartment of Gastroenterology and Hepatology, National Center for Global Health and Medicine (NCGM), Tokyo, Japan.
Ryo NakashimaDepartment of Gastroenterology and Hepatology, National Center for Global Health and Medicine (NCGM), Tokyo, Japan.
Hyung Hun KimDivision of Internal Medicine, Kosin University College of Medicine, Busan, Korea.
Takeichi YoshidaDepartment of Gastroenterology and Hepatology, Wakayama Medical University, Wakayama, Japan.
Kazufusa HoshimotoDepartment of Clinical Laboratory Pathological Division, NCGM, Tokyo, Japan.
Naomi UemuraDepartment of Gastroenterology and Hepatology, NCGM, Kohnodai Hospital, Chiba, Japan.
National Center for Global Health and Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntestinal metaplasia (IM) is regarded as a premalignant lesion. However, endoscopic diagnosis of IM has been considered difficult. Using endoscopy, we found a unique pattern of erythema, "Mottled Patchy Erythema (MPE)," which includes severe IM.

methodsWe enrolled patients with chronic gastritis who underwent successful

resultsA total of 102 patients were selected for the study. Of these, 55 (54%) patients had MPE. Biopsy specimens were taken from the MPE sites and non-MPE sites from these 55 patients. The IM percentages and median scores of IM were both significantly higher at the MPE sites (P < 0.001) than at the non-MPE sites. The sensitivity and specificity for MPE in the detection of histologic IM were 72.7% and 84.1%, respectively. No significant associations were observed in the expression of MUC2, MUC5AC, MUC6, CD10, and CDX2 between the MPE sites and non-MPE sites. There were no significant differences in the ratios (complete/incomplete) of IM subtypes between the two groups.

conclusionsMPE is a useful endoscopic finding to detect histologic IM without the use of chromoendoscopy and magnifying endoscopy. However, the IM subtype is difficult to identify. In the era of

Indexed as

Endoscopic findingErythemaHelicobacter pyloriIntestinal metaplasiaPremalignant lesionSubtype, eradicationWhite-light endoscopy

Identifiers

PMID27957016
PMCPMC5139844
OpenAlexW2041124149

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.