Evidence map›Paper›PMID 27956963›Full record

ArticleGastroenterology research2009

Bioinformatics Analysis and Validation of the Expressed Sequences Tag in Human Colorectal Adenocarcinoma.

Yao Chen, Chun Le Zhang, Yong Qiang Shen, Li Cheng Wang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastroenterology research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yao ChenDepartment of Anatomy, Basic Medical and Legal Medical Institute of Sichuan university. Chengdu, Sichuan, China. 610041.
Chun Le ZhangDepartment of Anatomy, Basic Medical and Legal Medical Institute of Sichuan university. Chengdu, Sichuan, China. 610041.
Yong Qiang ShenDepartment of Anatomy, Basic Medical and Legal Medical Institute of Sichuan university. Chengdu, Sichuan, China. 610041.
Li Cheng WangDepartment of Anatomy, Basic Medical and Legal Medical Institute of Sichuan university. Chengdu, Sichuan, China. 610041.
West China Medical Center of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study was to investigate some new pathological genes in colorectal adenocarcinoma of human.

methodsHuman colorectal adenocarcinoma tissues and normal colorectal tissues were taken and suppression subtractive hybridization (SSH) and cDNA microarray techniques were employed. From differentially expressed 86 expressed sequence tags (EST), 10 EST of the SSH were selected as seed sequence for bioinformatics analyses, semi-quantitative RT-PCR and PCR-sequencing. Each lane of semi-quantitative RT-PCR was analyzed by Q1 software.

resultsAmong these 10 EST, it has been found that ES274070, ES274071, ES274076 and ES274081 may play role in the onset of colorectal adenocarcinoma in human.

conclusionsThe ES274070, ES274071, ES274076 and ES274081 are related to the onset of human colorectal adenocarcinoma.

Indexed as

Bioinformatic analysesColorectal adenocarcinomaExpressed sequence tag

Identifiers

PMID27956963
PMCPMC5139827
OpenAlexW1986449731

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.