Evidence map›Paper›PMID 27956893›Full record

ReviewClinical and molecular allergy : CMA2016

Eosinophilic disorders of the gastro-intestinal tract: an update.

Erminia Ridolo, Valerie Melli, Gianluigi De' Angelis, Irene Martignago

Open access · goldAbstract readReview
In one paragraph

Review in Clinical and molecular allergy : CMA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Current and Novel Therapies for Eosinophilic Gastrointestinal Diseases.International journal of molecular sciences · 2023
    Review
  4. Article
  5. Eosinophilic gastroenteritis: Clinical characteristics and management.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Erminia RidoloDepartment of Clinical and Experimental Medicine, University of Parma, via Gramsci, 14, 43100 Parma, Italy.ORCID 0000-0003-1439-7902
Valerie MelliDepartment of Clinical and Experimental Medicine, University of Parma, via Gramsci, 14, 43100 Parma, Italy.
Gianluigi De' AngelisDepartment of Clinical and Experimental Medicine, University of Parma, via Gramsci, 14, 43100 Parma, Italy.
Irene MartignagoDepartment of Clinical and Experimental Medicine, University of Parma, via Gramsci, 14, 43100 Parma, Italy.
University of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic diseases of the gastrointestinal tract, including eosinophilic esophagitis (EoE) and eosinophilic gastroenteritis (EGE), are rare chronic pathologies of the digestive system, with an immuno-mediated pathogenesis. Recent data suggest that, together with the "classic" IgE-response to allergens, also a delayed hypersensitivity mechanism could be involved in the development of eosinophilic disorders. EoE and EGE were studied only in the latest decades and as a consequence accurate data are not yet available, concerning not only pathogenesis, but also epidemiology, treatment and outcomes. The diagnosis of EoE is centered on endoscopic findings but the certainty is obtained by histological examination from biopsy samples, that has a sensitivity of 100% when based on five samples. The currently available treatments include topical corticosteroids, specific diets and endoscopic treatment. Concerning EGE, three subtypes (mucosal, muscular, and serosal) were identified. The diagnosis is based, as for EoE, on endoscopic and histological assessment, and the treatment includes pharmacological and dietetic approaches. Further studies are warranted in order to better define the etiology and pathogenesis of eosinophilic diseases of the gastrointestinal tract, and thus to develop more appropriate and specific therapies.

Indexed as

DiagnosisEosinophilic esophagitisEosinophilic gastroenteritisPathogenesisTherapy

Identifiers

PMID27956893
PMCPMC5131414
OpenAlexW2551464286

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.