Evidence map›Paper›PMID 27956586›Full record

ArticleThe Plant cell2016

DNA Methylation Influences the Expression of DICER-LIKE4 Isoforms, Which Encode Proteins of Alternative Localization and Function.

Nathan Pumplin, Alexis Sarazin, Pauline E Jullien, Nicolas G Bologna, Stefan Oberlin, Olivier Voinnet

Open access · bronzeAbstract read
In one paragraph

Article in The Plant cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
13.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The plant siRNA landscape.The Plant cell · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. The Whys and Wherefores of Transitivity in Plants.Frontiers in plant science · 2020
    Review
  16. Article
  17. Review
  18. Article
  19. Extensive profiling inRNA (New York, N.Y.) · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nathan PumplinDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland voinneto@ethz.ch npumplin@ethz.ch.ORCID 0000-0003-4492-5358
Alexis SarazinDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland.
Pauline E JullienDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland.
Nicolas G BolognaDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland.ORCID 0000-0002-2161-7910
Stefan OberlinDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland.
Olivier VoinnetDepartment of Biology, ETH Zurich, 8092 Zurich, Switzerland voinneto@ethz.ch npumplin@ethz.ch.
ETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant RNA silencing operates via RNA-directed DNA-methylation (RdDM) to repress transcription or by targeting mRNAs via posttranscriptional gene silencing (PTGS). These pathways rely on distinct Dicer-like (DCL) proteins that process double-stranded RNA (dsRNA) into small-interfering RNAs (siRNAs). Here, we explored the expression and subcellular localization of Arabidopsis thaliana DCL4. DCL4 expression predominates as a transcription start site isoform encoding a cytoplasmic protein, which also represents the ancestral form in plants. A longer DCL4 transcript isoform encoding a nuclear localization signal, DCL4

Indexed as

DNA MethylationGene Expression Regulation, PlantArabidopsisArabidopsis ProteinsDNA Transposable ElementsProtein IsoformsRibonuclease IIIRNA-Dependent RNA PolymeraseRNA, Small InterferingArabidopsis ProteinsDCL4 protein, ArabidopsisDNA Transposable ElementsProtein IsoformsRibonuclease IIIRNA-Dependent RNA PolymeraseRNA, Small Interfering

Identifiers

PMID27956586
PMCPMC5155348
OpenAlexW2550837655

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.