Evidence map›Paper›PMID 27956548›Full record

ArticleThe Journal of biological chemistry2017

A Late G1 Lipid Checkpoint That Is Dysregulated in Clear Cell Renal Carcinoma Cells.

Deven Patel, Darin Salloum, Mahesh Saqcena, Amrita Chatterjee, Victoria Mroz, Michael Ohh, David A Foster

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. M-iScience · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Deven PatelFrom the Department of Biological Sciences, Hunter College of the City University of New York, New York, New York 10065.
Darin SalloumFrom the Department of Biological Sciences, Hunter College of the City University of New York, New York, New York 10065.
Mahesh SaqcenaFrom the Department of Biological Sciences, Hunter College of the City University of New York, New York, New York 10065.
Amrita ChatterjeeFrom the Department of Biological Sciences, Hunter College of the City University of New York, New York, New York 10065.
Victoria MrozFrom the Department of Biological Sciences, Hunter College of the City University of New York, New York, New York 10065.
Michael Ohhthe Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada.
David A FosterFrom the Department of Biological Sciences, Hunter College of the City University of New York, New York, New York 10065, foster@genectr.hunter.cuny.edu.
Hunter College · USThe Graduate Center, CUNY · USCity University of New York · USUniversity of Toronto · CA

Funding

Role of phospholipase D in tumorigenesisR01CA046677 · NCI · HUNTER COLLEGE · PI FOSTER, DAVID A · 1997 to 2014
$3.6M
Dysregulated Metabolic Cell Cycle Checkpoints in Human CancerR01CA179542 · NCI · HUNTER COLLEGE · PI FOSTER, DAVID A · 2014 to 2018
$1.3M
CIHR MOP-77718NCI NIH HHS R01 CA046677NCI NIH HHS R01 CA179542
6 · The paper itself

Abstract

Lipids are important nutrients that proliferating cells require to maintain energy homeostasis as well as to build plasma membranes for newly synthesized cells. Previously, we identified nutrient-sensing checkpoints that exist in the latter part of the G

Indexed as

G1 Phase Cell Cycle CheckpointsLipid MetabolismCarcinoma, Renal CellCell MembraneEndoplasmic Reticulum StressGlutamineHumansKidney NeoplasmsMCF-7 CellsNeoplasm ProteinsPTEN PhosphohydrolaseTOR Serine-Threonine KinasesGlutamineMTOR protein, humanNeoplasm ProteinsPTEN PhosphohydrolasePTEN protein, humanTOR Serine-Threonine Kinasesamino acidcell cyclecheckpoint controlcheckpointsglutaminelipidlipidsmTOR complex (mTORC)renal cancerSTART

Identifiers

PMID27956548
PMCPMC5247665
OpenAlexW2565251648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.