ArticleCirculation. Cardiovascular imaging2016
Functional Assessment of Coronary Artery Disease Using Whole-Heart Dynamic Computed Tomographic Perfusion.
Article in Circulation. Cardiovascular imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Reproducibility of a single-volume dynamic CT myocardial blood flow measurement technique: validation in a swine model.European radiology experimental · 2024Article
- Low-dose quantitative CT myocardial flow measurement using a single volume scan: phantom and animal validation.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- Evaluation and timing optimization of CT perfusion first pass analysis in comparison to maximum slope model in pancreatic adenocarcinoma.Scientific reports · 2023Article
- Dynamic CT myocardial perfusion without image registration.Scientific reports · 2022Article
- Contrast timing optimization of a two-volume dynamic CT pulmonary perfusion technique.Scientific reports · 2022Article
- Absolute cerebral blood flow: Assessment with a novel low-radiation-dose dynamic CT perfusion technique in a swine model.Journal of neuroradiology = Journal de neuroradiologie · 2022Article
- Combining perfusion and angiography with a low-dose cardiac CT technique: a preliminary investigation in a swine model.The international journal of cardiovascular imaging · 2021Article
- Comparison of automated beam hardening correction (ABHC) algorithms for myocardial perfusion imaging using computed tomography.Medical physics · 2021Article
- Dynamic pulmonary CT perfusion using first-pass analysis technique with only two volume scans: Validation in a swine model.PloS one · 2020Article
- Low-Radiation-Dose Stress Myocardial Perfusion Measurement Using First-Pass Analysis Dynamic Computed Tomography: A Preliminary Investigation in a Swine Model.Investigative radiology · 2019Article
- Timing optimization of low-dose first-pass analysis dynamic CT myocardial perfusion measurement: validation in a swine model.European radiology experimental · 2019Article
- The role of acquisition and quantification methods in myocardial blood flow estimability for myocardial perfusion imaging CT.Physics in medicine and biology · 2018Article
- CT Myocardial Perfusion Imaging: A New Frontier in Cardiac Imaging.BioMed research international · 2018Review
- Comprehensive Assessment of Coronary Artery Disease by Using First-Pass Analysis Dynamic CT Perfusion: Validation in a Swine Model.Radiology · 2018Article
- Validation of myocardial perfusion quantification by dynamic CT in an ex-vivo porcine heart model.The international journal of cardiovascular imaging · 2017Article
- Quantification of vessel-specific coronary perfusion territories using minimum-cost path assignment and computed tomography angiography: Validation in a swine model.Journal of cardiovascular computed tomographyArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundComputed tomographic (CT) angiography is an important tool for the evaluation of coronary artery disease but often correlates poorly with myocardial ischemia. Current dynamic CT perfusion techniques can assess ischemia but have limited accuracy and deliver high radiation dose. Therefore, an accurate, low-dose, dynamic CT perfusion technique is needed. METHODS AND
resultsA total of 20 contrast-enhanced CT volume scans were acquired in 5 swine (40±10 kg) to generate CT angiography and perfusion images. Varying degrees of stenosis were induced using a balloon catheter in the proximal left anterior descending coronary artery, and a pressure wire was used for reference fractional flow reserve (FFR) measurement. Perfusion measurements were made with only 2 volume scans using a new first-pass analysis (FPA) technique and with 20 volume scans using an existing maximum slope model (MSM) technique. Perfusion (P) and FFR measurements were related by P
conclusionsA new FPA-based dynamic CT perfusion technique was validated in a swine animal model. The results indicate that the FPA technique can potentially be used for improved anatomical and functional assessment of coronary artery disease at a relatively low radiation dose.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.