Evidence map›Paper›PMID 27956381›Full record

ArticleAmerican journal of physiology. Renal physiology2016

Hydrogen peroxide suppresses TRPM4 trafficking to the apical membrane in mouse cortical collecting duct principal cells.

Ming-Ming Wu, Yu-Jia Zhai, Yu-Xia Li, Qing-Qing Hu, Zhi-Rui Wang, Shi-Peng Wei, Li Zou, Abdel A Alli, Tiffany L Thai, Zhi-Ren Zhang and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. The odyssey of the TR(i)P journey to the cellular membrane.Frontiers in cell and developmental biology · 2024
    Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ming-Ming WuDepartments of Cardiology and Clinic Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Harbin, China; and.
Yu-Jia ZhaiDepartment of Physiology, Emory University School of Medicine, Atlanta, Georgia.
Yu-Xia LiDepartments of Cardiology and Clinic Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Harbin, China; and.
Qing-Qing HuDepartments of Cardiology and Clinic Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Harbin, China; and.
Zhi-Rui WangDepartments of Cardiology and Clinic Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Harbin, China; and.
Shi-Peng WeiDepartment of Physiology, Emory University School of Medicine, Atlanta, Georgia.
Li ZouDepartment of Physiology, Emory University School of Medicine, Atlanta, Georgia.
Abdel A AlliDepartment of Physiology, Emory University School of Medicine, Atlanta, Georgia.
Tiffany L ThaiDepartment of Physiology, Emory University School of Medicine, Atlanta, Georgia.
Zhi-Ren ZhangDepartments of Cardiology and Clinic Pharmacy, Harbin Medical University Cancer Hospital, Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Harbin, China; and zhirenz@yahoo.com.
He-Ping MaDepartment of Physiology, Emory University School of Medicine, Atlanta, Georgia.
Emory University · USThird Affiliated Hospital of Harbin Medical University · CNHarbin Medical University · CN

Funding

Role of Ion Channels in Kidney DiseasesR01DK100582 · NIDDK · EMORY UNIVERSITY · PI MA, HE-PING · 2014 to 2017
$1.4M
NIDDK NIH HHS R01 DK100582
6 · The paper itself

Abstract

A Ca

Indexed as

Adenosine TriphosphateAnimalsCalciumCell LineDose-Response Relationship, DrugHydrogen PeroxideIonomycinKidney Tubules, CollectingMicePhenanthrenesProtein Kinase InhibitorsProtein TransportTRPM Cation Channels9-phenanthrolAdenosine TriphosphateCalciumHydrogen PeroxideIonomycinPhenanthrenesProtein Kinase InhibitorsTRPM4 protein, mouseTRPM Cation ChannelsCa2+-activated nonselective cation channelconfocal microscopyintracellular calciumpatch clampreactive oxygen species

Identifiers

PMID27956381
PMCPMC5210207
OpenAlexW2550719226

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.