Evidence map›Paper›PMID 27955676›Full record

ArticleItalian journal of pediatrics2016

No effect of yeast-like fungi on lipid metabolism and vascular endothelial growth factor level in children and adolescents with type 1 diabetes mellitus.

Katarzyna Zorena, Beata Kowalewska, Małgorzata Szmigiero-Kawko, Piotr Wąż, Małgorzata Myśliwiec

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Italian journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Katarzyna ZorenaDepartment of Immunobiology and Environment Microbiology, Medical University of Gdańsk, Dębinki 7, Gdańsk, 80-211, Poland. kzorena@gumed.edu.pl.
Beata KowalewskaDepartment of Tropical Medicine and Epidemiology, Institute of Maritime and Tropical Medicine, Medical University of Gdańsk, Gdańsk, Poland.
Małgorzata Szmigiero-KawkoClinics of Paediatrics, Diabetology and Endocrinology, Medical University of Gdańsk, Gdańsk, Poland.
Piotr WążDepartment of Nuclear Medicine, Medical University of Gdańsk, Gdańsk, Poland.
Małgorzata MyśliwiecClinics of Paediatrics, Diabetology and Endocrinology, Medical University of Gdańsk, Gdańsk, Poland.
Gdańsk Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of the research was to investigate vascular endothelial growth factor (VEGF) levels in the context of lipid metabolism and amount of yeast-like fungi colonizing the digestive tract in children and adolescents with type 1 diabetes mellitus (T1DM).

methodsThe study included 45 children with T1DM and 27 age- and sex-matched healthy control subjects. In the study sample 33 T1DM patients were administered insulin pump therapy and 12 T1DM patients were administered multiple daily injections with insulin pen devices. All T1DM patients were free of micro- and macrovascular complications. In T1DM patients and healthy controls biochemical tests were performed and measurements of yeast-like fungi colonizing the alimentary tract were conducted. Moreover all study subjects had their serum VEGF levels measured with ELISA test.

resultsThe subgroup of children and adolescents with T1DM and yeast-like fungus colony number 10^

conclusionsOur study has shown no influence of yeast-like fungi on lipid metabolism and VEGF level in children and adolescents with T1DM. Comprehensive treatment of T1DM patients and intensive insulin therapy with help of personal insulin pumps can reduce or prevent the development of long-term diabetic complications. Further studies in this field are needed.

Indexed as

AdolescentCase-Control StudiesChildDiabetes Mellitus, Type 1Enzyme-Linked Immunosorbent AssayFemaleHumansHypoglycemic AgentsInfusion PumpsInsulinLipid MetabolismMaleMycosesVascular Endothelial Growth Factor AHypoglycemic AgentsInsulinVascular Endothelial Growth Factor AChildren and adolescentsLipid metabolismType 1 diabetes mellitusVascular endothelial growth factorYeast-like fungi

Identifiers

PMID27955676
PMCPMC5153819
OpenAlexW2567359606

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.