ArticlePharmaceutical biology2017
Studies on phytochemical, antioxidant, anti-inflammatory, hypoglycaemic and antiproliferative activities of Echinacea purpurea and Echinacea angustifolia extracts.
Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 108 citations in OpenAlex.
- Trial
- Ameliorative effects of Spirulina platensis niosome and Echinacea purpura on cyclophosphamide-induced splenic, cardiac and neurotoxicity via modulating NF-κB pathway and oxidative stress.Scientific reports · 2026Article
- Interactive Effects of Polyamines and Plant Growth Regulators on Shoot Induction and Secondary Metabolism inMolecules (Basel, Switzerland) · 2026Article
- Pharmacological Insights and Technological Innovations inPharmaceuticals (Basel, Switzerland) · 2026Review
- Impact of Bacterial Fermentation on Phytochemical Profile and Bioactivity ofInternational journal of food science · 2026Article
- Influence of Freeze- and Spray Drying with Carrier Agents on Alkamides, Antioxidant Properties, and Process Contaminants inMolecules (Basel, Switzerland) · 2025Article
- Article
- Effect ofFood chemistry: X · 2025Article
- First-Time Identification of the PPAT Protein as a Novel Antibacterial Target: Antimicrobial and Antioxidant Insights from E. purpurea.ACS omega · 2025Article
- Phytochemical Composition and Wound Healing Properties ofInternational journal of molecular sciences · 2025Article
- Investigating potent cardioprotective compounds as ACE inhibitors inToxicology reports · 2024Review
- Phytochemistry, Mechanisms, and Preclinical Studies of Echinacea Extracts in Modulating Immune Responses to Bacterial and Viral Infections: A Comprehensive Review.Antibiotics (Basel, Switzerland) · 2024Review
- Improvement ofMolecules (Basel, Switzerland) · 2024Article
- Polyphenolic Characterization and Anti-Inflammatory Effect of In Vitro Digested Extracts ofInternational journal of molecular sciences · 2024Article
- Echinacea purpurea extract intervention for counteracting neurochemical and behavioral changes induced by bifenthrin.Metabolic brain disease · 2024Article
- Article
- ECHOPvir: A Mixture of Echinacea and Hop Extracts Endowed with Cytoprotective, Immunomodulatory and Antiviral Properties.Nutrients · 2023Article
- Effects ofNutrition research and practice · 2023Article
- Determination of the Bioactive Compounds fromMolecules (Basel, Switzerland) · 2023Article
- Nutraceuticals as Modulators of Immune Function: A Review of Potential Therapeutic Effects.Preventive nutrition and food science · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextEchinacea (Asteraceae) is used because of its pharmacological properties. However, there are few studies that integrate phytochemical analyses with pharmacological effects.
objectiveEvaluate the chemical profile and biological activity of hydroalcoholic Echinacea extracts. MATERIALS AND
methodsDensity, dry matter, phenols (Folin-Ciocalteu method), flavonoids (AlCl
resultsExtract C showed higher density (0.97 g/mL), dry matter (0.23 g/mL), phenols (137.5 ± 2.3 mEAG/mL), flavonoids (0.62 ± 0.02 mEQ/mL), and caffeic acid (0.048 mg/L) compared to A and B. A, B presented 11 alkylamides, whereas C presented those 11 and three more. B decreased the oedema (40%) on day 2 similar to indomethacin. A and C showed hypoglycaemic activity similar to glibenclamide. Antiproliferative effect was only detected for C (IC DISCUSSION AND
conclusionThe difference in the chemical and pharmacological properties among extracts highlights the need to consider strategies and policies for standardization of commercial herbal extracts in order to guarantee the safety and identity of this type of products.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.