ArticlePharmaceutical biology2017
Phytochemical, antioxidant and protective effect of cactus cladodes extract against lithium-induced liver injury in rats.
Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 55 citations in OpenAlex.
- Modulation of human neutrophil functions by hydroethanolic cladode extract of Opuntia ficus-indica: an in vitro experimental study.BMC complementary medicine and therapies · 2025Article
- Hepatoprotective Properties ofFood science & nutrition · 2025Article
- Identification, Quantification, and Antioxidant Evaluation of Phenolic Compounds from ColoredAntioxidants (Basel, Switzerland) · 2025Article
- Opuntia ficus-indica cladodes extract inhibits human neutrophil pro-inflammatory functions and protects rats from acetic acid-induced ulcerative colitis.Inflammopharmacology · 2024Article
- Cytoprotective potential ofOpen veterinary journal · 2024Article
- Antioxidant and Anti-Inflammatory Effects ofAntioxidants (Basel, Switzerland) · 2024Article
- Structure-Function Relationships and Health-Promoting Properties of the Main Nutraceuticals of the Cactus Pear (Molecules (Basel, Switzerland) · 2024Review
- In vivo anti-Salmonella properties of aqueous extract of prickly pear (Food science & nutrition · 2024Article
- Cladodes ofPlants (Basel, Switzerland) · 2024Article
- The reprotoxic adverse side effects of neurogenic and neuroprotective drugs: current use of human organoid modeling as a potential alternative to preclinical models.Frontiers in pharmacology · 2024Review
- Lithium Treatment Induces Cardiac Dysfunction in Mice.International journal of molecular sciences · 2023Article
- Beneficial Effects ofAntioxidants (Basel, Switzerland) · 2023Review
- Supplementation of feedlot lambs with cactus cladodes as strategy to improve testicular function.Tropical animal health and production · 2023Article
- Review
- Phytochemical Analysis and Genotoxicological Evaluation of Prickly Pear Peel Extracts.Plants (Basel, Switzerland) · 2023Article
- A Study on the Time-Effect and Dose-Effect Relationships of Polysaccharide fromFoods (Basel, Switzerland) · 2022Article
- Over-Dose Lithium Toxicity as an Occlusive-like Syndrome in Rats and Gastric Pentadecapeptide BPC 157.Biomedicines · 2021Article
- Hepatoprotective and Antioxidant Capacity ofACS omega · 2021Article
- The activation of nuclear factor-E2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) signaling blunts cholestasis-induced liver and kidney injury.Toxicology research · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextOpuntia ficus-indica (L.) Mill. (Castaceae) (cactus) is used in Tunisian medicine for the treatment of various diseases.
objectiveThis study determines phytochemical composition of cactus cladode extract (CCE). It also investigates antioxidant activity and hepatoprotective potential of CCE against lithium carbonate (Li MATERIALS AND
methodsTwenty-four Wistar male rats were divided into four groups of six each: a control group given distilled water (0.5 mL/100 g b.w.; i.p.), a group injected with Li
resultsTreatment with Li
conclusionCCE possesses a significant hepatoprotective effect.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.