Evidence map›Paper›PMID 27943485›Full record

ArticleThe Plant journal : for cell and molecular biology2017

Maintaining the factory: the roles of the unfolded protein response in cellular homeostasis in plants.

Evan Angelos, Cristina Ruberti, Sang-Jin Kim, Federica Brandizzi

Open access · bronzeAbstract readEditorial
In one paragraph

Article in The Plant journal : for cell and molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 71 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Organelle Communication with the Nucleus.Results and problems in cell differentiation · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. CRISPR/Cas9-MediatedInternational journal of molecular sciences · 2023
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Novel molecules and target genes for vegetative heat tolerance in wheat.Plant-environment interactions (Hoboken, N.J.) · 2022
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Evan AngelosMSU-DOE Plant Research Lab and Plant Biology Department, Michigan State University, East Lansing, MI, 48824, USA.ORCID http://orcid.org/0000-0002-1335-5463
Cristina RubertiMSU-DOE Plant Research Lab and Plant Biology Department, Michigan State University, East Lansing, MI, 48824, USA.
Sang-Jin KimMSU-DOE Plant Research Lab and Plant Biology Department, Michigan State University, East Lansing, MI, 48824, USA.
Federica BrandizziMSU-DOE Plant Research Lab and Plant Biology Department, Michigan State University, East Lansing, MI, 48824, USA.
Carnegie Department of Plant Biology · USGreat Lakes Bioenergy Research Center · US

Funding

Unfolded protein response in the model species Arabidopsis thalianaR01GM101038 · NIGMS · MICHIGAN STATE UNIVERSITY · PI BRANDIZZI, FEDERICA · 2012 to 2019
$2.5M
Plant Biotechnology for Health and SustainabilityT32GM110523 · NIGMS · MICHIGAN STATE UNIVERSITY · PI LAST, ROBERT LOUIS · 2014 to 2023
$2.2M
NIGMS NIH HHS R01 GM101038NIGMS NIH HHS T32 GM110523
6 · The paper itself

Abstract

Much like a factory, the endoplasmic reticulum (ER) assembles simple cellular building blocks into complex molecular machines known as proteins. In order to protect the delicate protein folding process and ensure the proper cellular delivery of protein products under environmental stresses, eukaryotes have evolved a set of signaling mechanisms known as the unfolded protein response (UPR) to increase the folding capacity of the ER. This process is particularly important in plants, because their sessile nature commands adaptation for survival rather than escape from stress. As such, plants make special use of the UPR, and evidence indicates that the master regulators and downstream effectors of the UPR have distinct roles in mediating cellular processes that affect organism growth and development as well as stress responses. In this review we outline recent developments in this field that support a strong relevance of the UPR to many areas of plant life.

Indexed as

ArabidopsisArabidopsis ProteinsEndoplasmic Reticulum StressHomeostasisSignal TransductionUnfolded Protein ResponseArabidopsis ProteinsArabidopsis thalianabZIP28bZIP60ER stressIRE1unfolded protein response

Identifiers

PMID27943485
PMCPMC5415411
OpenAlexW2560211886

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.