ReviewCNS drugs2017
Targeting Functional Impairments in the Treatment of Children and Adolescents with ADHD.
Review in CNS drugs, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Conceptual review of measuring functional impairment: findings from the Weiss Functional Impairment Rating Scale.Evidence-based mental health · 2018Pooled it
- Clinically Meaningful Improvements in Early Morning and Late Afternoon/Evening Functional Impairment in Children with ADHD Treated with Delayed-Release and Extended-Release Methylphenidate.Journal of attention disorders · 2022Trial
- A Randomized, Double-Blind, Placebo-Controlled Study of HLD200, a Delayed-Release and Extended-Release Methylphenidate, in Children with Attention-Deficit/Hyperactivity Disorder: An Evaluation of Safety and Efficacy Throughout the Day and Across Settings.Journal of child and adolescent psychopharmacology · 2020Trial
- Efficacy and Safety of HLD200, Delayed-Release and Extended-Release Methylphenidate, in Children with Attention-Deficit/Hyperactivity Disorder.Journal of child and adolescent psychopharmacology · 2017Trial
- Efficacy of the digital health application ORIKOMethodsX · 2026Article
- Article
- From ADHD symptoms to parental stress: The roles of functional impairment, family functioning, and parental ADHD.PloS one · 2026Article
- Efficacy and Compliance of a Working Memory Multitasking Task Mobile Intervention for Children With Attention-Deficit/Hyperactivity Disorder: Single-Arm, Pre-Post Pilot Study.JMIR human factors · 2025Article
- ADHD drug treatment and risk of suicidal behaviours, substance misuse, accidental injuries, transport accidents, and criminality: emulation of target trials.BMJ (Clinical research ed.) · 2025Article
- Assessing the Impact of Serum Ferritin on Life Skills in Children with ADHD.Children (Basel, Switzerland) · 2025Article
- A Randomized Clinical Trial Comparing the Effectiveness of Emotion-Focused and Behavioral Parent Training in Families of School-aged Children with Attention-Deficit/Hyperactivity Disorder.Child psychiatry and human development · 2025Article
- Associations Between Peer Victimization and Aggression and Three Types of Domestic Violence in Adolescents with Attention-Deficit/Hyperactivity Disorder.Children (Basel, Switzerland) · 2025Article
- Bias by gender: exploring gender-based differences in the endorsement of ADHD symptoms and impairment among adult patients.Frontiers in global women's health · 2025Article
- Impairment Assessment in Adult ADHD and Related Disorders: Current Opinions From Clinic and Research.Journal of attention disorders · 2024Article
- Article
- Article
- Internet Altruistic Behaviors in Adolescents: Roles of Attention-Deficit/Hyperactivity Disorder, Impulsiveness, and Perceived Social Support.Behavioral sciences (Basel, Switzerland) · 2024Article
- Parent training for disruptive behavior symptoms in attention deficit hyperactivity disorder: a randomized clinical trial.Frontiers in psychology · 2024Article
- A Paradigm for Targeting Functional Impairment as an Outcome in Attention-Deficit/Hyperactivity Disorder.Brain sciences · 2022Article
- Associated predictors of functional impairment among adolescents with ADHD-a cross-sectional study.Child and adolescent psychiatry and mental health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnostic criteria for attention-deficit hyperactivity disorder (ADHD) require both symptoms and impairment to be present. Impairment in functioning is commonly the primary reason for referral, and is also a better predictor of long-term outcomes than ADHD symptoms. And yet, only recently has research begun to examine the impact of ADHD treatments on functional impairment using efficient and psychometrically sound outcome measures. In this article, we identify several noteworthy multidimensional measures of functional impairment (ADHD FX, Barkley Functional Impairment Scale [BFIS], Impairment Rating Scale [IRS], Weiss Functional Impairment Rating Scale [WFIRS]) utilized in recent clinical trials for ADHD, and describe their psychometric properties and clinical utility. We also review existing evidence on the impact of pharmacological and behavioral treatments on different domains of functional impairment in ADHD youth as measured by these specific measures. Further research is needed to evaluate longitudinal effects of ADHD treatments on functional impairment, and the use of these measures in adaptive treatment designs.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.