ArticleJournal of assisted reproduction and genetics2017
Morphokinetics of vitrified and warmed blastocysts predicts implantation potential.
Article in Journal of assisted reproduction and genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Towards Improving Embryo Prioritization: Parallel Next Generation Sequencing of DNA and RNA from a Single Trophectoderm Biopsy.Scientific reports · 2019Trial
- Ice-free vitrification of embryos and its impact on post-warming outcomes.Scientific reports · 2026Article
- Predictive Ability of an Objective and Time-Saving Blastocyst Scoring Model on Live Birth.Biomedicines · 2025Article
- "Try until the last?"-the relevance of fresh embryo transfer outcomes for subsequent same-cohort vitrified-warmed cycles.Journal of assisted reproduction and genetics · 2024Article
- Morphokinetic Profiling Suggests That Rapid First Cleavage Division Accurately Predicts the Chances of Blastulation in Pig In Vitro Produced Embryos.Animals : an open access journal from MDPI · 2024Article
- How great thou ART: biomechanical properties of oocytes and embryos as indicators of quality in assisted reproductive technologies.Frontiers in cell and developmental biology · 2024Review
- Pre-Vitrification and Post-Warming Variables of Vitrified-Warmed Blastocysts That Are Predictable for Implantation.Journal of clinical medicine · 2023Article
- Clinical Usability of Embryo Development Using a Combined Qualitative and Quantitative Approach in a Single Vitrified-Warmed Blastocyst Transfer: Assessment of Pre-Vitrified Blastocyst Diameter and Post-Warmed Blastocyst Re-Expansion Speed.Journal of clinical medicine · 2022Article
- Time-Lapse Embryo culture: A better understanding of embryo development and clinical application.JBRA assisted reproduction · 2022Review
- Standardization of Post-Vitrification Human Blastocyst Expansion as a Tool for Implantation Prediction.Journal of clinical medicine · 2022Article
- Post-warming embryo morphology is associated with live birth: a cohort study of single vitrified-warmed blastocyst transfer cycles.Journal of assisted reproduction and genetics · 2022Article
- Comparison of pregnancy outcomes using a time-lapse monitoring system for embryo incubation versus a conventional incubator in in vitro fertilization: An age-stratification analysis.Clinical and experimental reproductive medicine · 2021Article
- The impact of post-warming culture duration on clinical outcomes of vitrified-warmed single blastocyst transfer cycles.Clinical and experimental reproductive medicine · 2020Article
- Observational
- Good practice recommendations for the use of time-lapse technologyHuman reproduction open · 2020Article
- HighJournal of animal science and biotechnology · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIt was studied whether morphokinetics of blastocoele re-expansion and hatching in vitrified-warmed blastocysts is predictive of implantation, clinical pregnancy, and live birth.
methodsIn 144 patients aiming for single warmed blastocyst transfer, blastocysts were cultured in a new time-lapse system (Miri® TL) immediately after warming. Video sequences with an image interval of 5 min were annotated and the corresponding morphokinetic variables were correlated with pregnancy outcome. In detail, tRE (start of re-expansion), tCRE (completion of re-expansion), tAH (hatching from the manipulated zona pellucida), and presence of collapses were recorded.
resultsIn the pregnant group, tRE and tCRE were significantly lower (0.69 ± 0.45 h and 2.16 ± 0.94 h) as compared to the non-pregnant group (1.23 ± 1.08 h and 2.70 ± 1.20 h). Both variables and the duration of re-expansion (tCRE-tRE) allowed for distinction between "non-pregnant," "loss of pregnancy," and live birth/ongoing pregnancy. Presence and number of collapses showed no correlation with outcome.
conclusionsTime-lapse imaging of vitrified-warmed blastocysts offers additional selection criteria allowing for prediction of implantation potential. As a consequence, cumulative pregnancy rate could be increased and time-to-pregnancy reduced.
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