Trial reportThe journal of primary prevention2017
Substance Use Prevention for Urban American Indian Youth: A Efficacy Trial of the Culturally Adapted Living in 2 Worlds Program.
Trial report in The journal of primary prevention, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Mixed methods systematic review: Using a cultural validity assessment to evaluate prevention programs for Indigenous students.Journal of school psychology · 2025Pooled it
- Preventing Substance Use Among Indigenous Adolescents in the USA, Canada, Australia and New Zealand: a Systematic Review of the Literature.Prevention science : the official journal of the Society for Prevention Research · 2020Pooled it
- Drug Use Prevention in Low-income Neighborhoods of Montevideo-Uruguay: the Effectiveness of Mantente REAL in Public Elementary Schools.Journal of prevention (2022) · 2026Trial
- The Fuetsan Manhoben Curriculum: Effects on Risk Perceptions and Intentions Regarding Tobacco and Betel Nut Use Among Adolescents in Guam.Substance use & misuse · 2026Trial
- Short-Term Secondary Effects of a School-Based Drug Prevention Program: Cluster-Randomized Controlled Trial of the Brazilian Version of DARE's Keepin' it REAL.Prevention science : the official journal of the Society for Prevention Research · 2022Trial
- Motivational interviewing and culture for urban Native American youth (MICUNAY): A randomized controlled trial.Journal of substance abuse treatment · 2020Trial
- Effectiveness of School-Based Integrated Mental Health and Substance Use Prevention Programs for Adolescents: A Systematic Review and Meta-Analysis.Behavioral sciences (Basel, Switzerland) · 2026Review
- Bridging traditions and prevention: Insights into implementing and sustaining substance use programs for urban AI/AN communities.Journal of substance use and addiction treatment · 2026Article
- Addressing substance use and mental illness among Quinault Indian Nation adolescents and young adults: community perspectives on community and cultural connection.Addiction science & clinical practice · 2026Article
- Youth vaping prevention with urban Indigenous communities of the southwest U.S.: a protocol for a randomized controlled trial.Frontiers in public health · 2025Article
- Addressing the needs for cultural adaptation of DARE-keepin' it REAL among Brazilian students: strategies to improve implementation.Substance abuse treatment, prevention, and policy · 2024Article
- Family ties: examining family functioning and alcohol use among American Indian youth.Drugs, habits and social policy · 2023Article
- Types of Offers of Combustible Cigarettes, E-Cigarettes, and Betel Nut Experienced by Guam Youths.International journal of environmental research and public health · 2023Article
- Intersecting sex and American Indian identity moderates school and individual correlates of binge drinking among reservation-area adolescents.Journal of psychopathology and clinical science · 2023Article
- Guam Adolescents' Use of Strategies to Resist Cigarette, e-Cigarette, and Betel Nut Offers: Findings from a Focus Group Study.Substance use & misuse · 2023Article
- Cultural Protection from Polysubstance Use Among Native American Adolescents and Young Adults.Prevention science : the official journal of the Society for Prevention Research · 2022Article
- Native Spirit: Development of a culturally grounded after-school program to promote well-being among American Indian adolescents.American journal of community psychology · 2022Article
- A Longitudinal Study of Alcohol and Cannabis Use in Young Adulthood: Exploring Racial and Ethnic Differences in the Effects of Peer and Parental Influences From Middle Adolescence.Journal of studies on alcohol and drugs · 2022Article
- Applying a Pattern-Centered Approach to Assess the Effect of a School-Based Drug Use Prevention Program in Brazil: A Cluster Randomized Controlled Trial.Journal of prevention (2022) · 2022Article
- Participation in a Culturally Grounded Program Strengthens Cultural Identity, Self-esteem, and Resilience in Urban Indigenous Adolescents.American Indian and Alaska native mental health research (Online) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
This article describes a small efficacy trial of the Living in 2 Worlds (L2W) substance use prevention curriculum, a culturally adapted version of keepin' it REAL (kiR) redesigned for urban American Indian (AI) middle school students. Focused on strengthening resiliency and AI cultural engagement, L2W teaches drug resistance skills, decision making, and culturally grounded prevention messages. Using cluster random assignment, the research team randomized three urban middle schools with enrichment classes for AI students. AI teachers of these classes delivered the L2W curriculum in two schools; the remaining school implemented kiR, unadapted, and became the comparison group. AI students (N = 107) completed a pretest questionnaire before they received the manualized curriculum lessons, and a posttest (85% completion) 1 month after the final lesson. We assessed the adapted L2W intervention, compared to kiR, with paired t tests, baseline adjusted general linear models, and effect size estimates (Cohen's d). Differences between the L2W and kiR groups reached statistically significant thresholds for four outcomes. Youth receiving L2W, compared to kiR, reported less growth in cigarette use from pretest to posttest, less frequent use of the Leave drug resistance strategy, and less loss of connections to AI spirituality and cultural traditions. For other substance use behaviors and antecedents, the direction of the non-significant effects in small sample tests was toward more positive outcomes in L2W and small to medium effect sizes. Results suggest that evidence-based substance use prevention programs that are culturally adapted for urban AI adolescents, like L2W, can be a foundation for prevention approaches to help delay initiation and slow increases in substance use. In addition to study limitations, we discuss implementation challenges in delivering school-based interventions for urban AI populations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.