ReviewReviews in endocrine & metabolic disorders2016
Carney complex: A familial lentiginosis predisposing to a variety of tumors.
Review in Reviews in endocrine & metabolic disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 78 citations in OpenAlex.
- Genetic testing in pituitary adenomas: a Pituitary Society International Consensus Statement.Nature reviews. Endocrinology · 2026Review
- PRKAR1A-related acrodysostosis with partial growth hormone deficiency: 18-month response to recombinant human growth hormone.Hormones (Athens, Greece) · 2026Review
- Guidelines on reporting epidemiological observational studies and their proper use in endocrine research.Hormones (Athens, Greece) · 2026Article
- Carney complex with PRKAR1A variant and breast/fibrolamellar carcinomas.Human genome variation · 2026Article
- Atypical Presentation and Course of ACTH-Independent Cushing’s Syndrome in Two FamiliesJournal of clinical research in pediatric endocrinology · 2026Article
- Cardiac Complications in Carney Complex: Right Ventricular Outflow Tract Obstruction and Pulmonary Hypertension.CASE (Philadelphia, Pa.) · 2025Article
- Rare large sigmoid hamartomatous polyp in an elderly patient with atypical Peutz-Jeghers syndrome: A case report.World journal of gastrointestinal surgery · 2025Article
- From cortisol-producing adrenal adenoma to atrial myxoma, through nivolumab-induced hypophysitis: a complicated case report of Carney Complex.Endocrine · 2024Article
- Molecular pathology of endocrine gland tumors: genetic alterations and clinicopathologic relevance.Virchows Archiv : an international journal of pathology · 2024Review
- Major Genetic Motifs in Pituitary Adenomas: A Practical Literature Update.World neurosurgery · 2023Review
- Case Report: Atrial myxoma combined with hyperthyroidism in an adolescent with literature review.Frontiers in oncology · 2023Article
- [Superficial angiomyxoma in nasal vestibule: a case report].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022Article
- Carney complex with multiple breast tumours including breast cancer: a case report.Oxford medical case reports · 2022Article
- Testicular Sertoli cell tumour and potentially testicular Leydig cell tumour are features ofJournal of medical genetics · 2022Article
- A novel mutation inArchives of endocrinology and metabolism · 2021Article
- First SomaticJournal of the Endocrine Society · 2021Article
- Visualization and bibliometric analysis of cAMP signaling system research trends and hotspots in cancer.Journal of Cancer · 2021Article
- Liver findings in patients with Carney complex, germline PRKAR1A pathogenic variants, and link to cardiac myxomas.Endocrine-related cancer · 2020Article
- Cushing syndrome: Old and new genes.Best practice & research. Clinical endocrinology & metabolism · 2020Review
- Obstetric and Neonatal Outcome of Pregnancy in Carney Complex: A Case Report.Frontiers in endocrinology · 2020Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Carney complex is a familial lentiginosis syndrome; these disorders cover a wide phenotypic spectrum ranging from a benign inherited predisposition to develop cutaneous spots not associated with systemic disease to associations with several syndromes. Carney complex is caused by PRKAR1A mutations and perturbations of the cyclic AMP-dependent protein kinase (PKA) signaling pathway. In addition to the cutaneous findings, the main tumors associated with Carney complex are endocrine: 1) primary pigmented nodular adrenocortical disease, a bilateral adrenal hyperplasia leading to Cushing syndrome; 2) growth-hormone secreting pituitary adenoma or pituitary somatotropic hyperplasia leading to acromegaly; 3) thyroid and gonadal tumors, including a predisposition to thyroid cancer. Other tumors associated with Carney complex include: 1) myxomas of the heart, breast and other sites; 2) psamommatous melanotic schwannomas which can become malignant; 4) a predisposition to a variety of cancers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.