Evidence map›Paper›PMID 27942993›Full record

ArticleThe journal of physiological sciences : JPS2017

Diadenosine pentaphosphate affects electrical activity in guinea pig atrium via activation of potassium acetylcholine-dependent inward rectifier.

Denis V Abramochkin, Viktoria M Karimova, Tatiana S Filatova, Andre Kamkin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of physiological sciences : JPS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Characterization of hERG KNaunyn-Schmiedeberg's archives of pharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Denis V AbramochkinDepartment of Human and Animal Physiology, Lomonosov Moscow State University, Leninskiye Gory, 1, 12, Moscow, Russia. abram340@mail.ru.ORCID http://orcid.org/0000-0001-5751-8853
Viktoria M KarimovaDepartment of Human and Animal Physiology, Lomonosov Moscow State University, Leninskiye Gory, 1, 12, Moscow, Russia.
Tatiana S FilatovaDepartment of Human and Animal Physiology, Lomonosov Moscow State University, Leninskiye Gory, 1, 12, Moscow, Russia.
Andre KamkinDepartment of Physiology, Pirogov Russian National Research Medical University, Moscow, Russia.
Lomonosov Moscow State University · RUPirogov Russian National Research Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diadenosine pentaphosphate (Ap5A) belongs to the family of diadenosine polyphosphates, endogenously produced compounds that affect vascular tone and cardiac performance when released from platelets. The previous findings indicate that Ap5A shortens action potentials (APs) in rat myocardium via activation of purine P2 receptors. The present study demonstrates alternative mechanism of Ap5A electrophysiological effects found in guinea pig myocardium. Ap5A (10

Indexed as

AcetylcholineAction PotentialsAnimalsAtrial FunctionDinucleoside PhosphatesGuinea PigsHeart AtriaHeart RateMalePotassiumPotassium Channels, Inwardly RectifyingPurinergic P1 Receptor AgonistsReceptors, Purinergic P1Species SpecificityTime FactorsAcetylcholineDinucleoside PhosphatesP(1),P(5)-di(adenosine-5'-)pentaphosphatePotassiumPotassium Channels, Inwardly RectifyingPurinergic P1 Receptor AgonistsReceptors, Purinergic P1Action potentialAtriumDiadenosine pentaphosphateGuinea pigHeartI KAChIonic currentPurine receptors

Identifiers

PMID27942993
PMCPMC10717602
OpenAlexW2559785112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.