Evidence map›Paper›PMID 27942984›Full record

ArticleImmunologic research2017

LPS-treated bone marrow-derived dendritic cells induce immune tolerance through modulating differentiation of CD4

Fang Zhou, Guang-Xian Zhang, Abdolmohamad Rostami

Open access · greenAbstract read
In one paragraph

Article in Immunologic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fang ZhouDepartment of Neurology, Thomas Jefferson University, 900 Walnut Street, Philadelphia, PA, 19107, USA.
Guang-Xian ZhangDepartment of Neurology, Thomas Jefferson University, 900 Walnut Street, Philadelphia, PA, 19107, USA.
Abdolmohamad RostamiDepartment of Neurology, Thomas Jefferson University, 900 Walnut Street, Philadelphia, PA, 19107, USA. a.m.rostami@jefferson.edu.
Thomas Jefferson University · US

Funding

Mechanisms of GM-CSF effect in CNS autoimmune demyelinationR01AI124386 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI ROSTAMI, A.M. · 2017 to 2021
$1.9M
The role of IL-27 in iv tolerance in EAER01AI106026 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI ROSTAMI, A.M. · 2014 to 2018
$1.9M
NSCs produce a triply effective cocktail in the CNS for MS/EAE therapyR01NS075260 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI ZHANG, GUANG-XIAN · 2012 to 2016
$1.5M
NIAID NIH HHS R01 AI106026NIAID NIH HHS R01 AI124386NINDS NIH HHS R01 NS075260
6 · The paper itself

Abstract

Intravenous transfer of LPS-treated bone marrow-derived dendritic cells blocks development of autoimmunity induced by CD4

Indexed as

AnimalsAntigens, SurfaceBone Marrow CellsCD4 AntigensCell DifferentiationCells, CulturedDendritic CellsEncephalomyelitis, Autoimmune, ExperimentalFemaleForkhead Transcription FactorsGlucocorticoid-Induced TNFR-Related ProteinHumansImmune ToleranceImmunomodulationInterleukin-2 Receptor alpha SubunitInterleukin-7 Receptor alpha Subunitantigen 3G11, mouseAntigens, SurfaceCD4 AntigensForkhead Transcription FactorsFoxp3 protein, mouseGlucocorticoid-Induced TNFR-Related ProteinInterleukin-2 Receptor alpha SubunitInterleukin-7 Receptor alpha SubunitLipopolysaccharidesMyelin-Oligodendrocyte Glycoproteinmyelin oligodendrocyte glycoprotein (35-55)Peptide FragmentsTnfrsf18 protein, mouseCD4+ T cellDendritic cellEAEImmune tolerance

Identifiers

PMID27942984
PMCPMC5533279
OpenAlexW2560519736

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.