ReviewPflugers Archiv : European journal of physiology2017
One gene, two paracellular ion channels-claudin-10 in the kidney.
Review in Pflugers Archiv : European journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 29 citations in OpenAlex.
- Ion and water permeation through claudin-10b and claudin-15 paracellular channels.Computational and structural biotechnology journal · 2024Article
- Tight junction and kidney stone disease.Tissue barriers · 2024Review
- Impact of claudin-10 deficiency on amelogenesis: Lesson from a HELIX tooth.Annals of the New York Academy of Sciences · 2022Article
- Defective claudin-10 causes a novel variation of HELIX syndrome through compromised tight junction strand assembly.Genes & diseases · 2022Article
- Article
- Pathophysiological aspects of the thick ascending limb and novel genetic defects: HELIX syndrome and transient antenatal Bartter syndrome.Pediatric nephrology (Berlin, Germany) · 2022Review
- Dysregulated expression of claudins in cancer.Oncology letters · 2021Review
- [A review on the effect of Claudin-18 on bronchopulmonary dysplasia in preterm infants].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Review
- Article
- Expression Patterns ofFrontiers in cell and developmental biology · 2020Article
- A Novel Claudinopathy Based on Claudin-10 Mutations.International journal of molecular sciences · 2019Review
- E-Cigarette Exposure Delays Implantation and Causes Reduced Weight Gain in Female Offspring ExposedJournal of the Endocrine Society · 2019Article
- Novel Aspects of Renal Magnesium Homeostasis.Frontiers in pediatrics · 2018Review
- A Novel Hypokalemic-Alkalotic Salt-Losing Tubulopathy in Patients withJournal of the American Society of Nephrology : JASN · 2017Article
- Tight junctions of the proximal tubule and their channel proteins.Pflugers Archiv : European journal of physiology · 2017Review
- Developmental Expression of Claudins in the Mammary Gland.Journal of mammary gland biology and neoplasia · 2017Article
- Claudins: vital partners in transcellular and paracellular transport coupling.Pflugers Archiv : European journal of physiology · 2017Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Claudins are tight junction membrane proteins and regulate the paracellular passage of ions and water. They can seal the paracellular cleft against solute passage but also form paracellular channels. They are tetraspan proteins with two extracellular segments. Claudin-10 exists in at least two functional isoforms, claudin-10a and claudin-10b, that differ in their first transmembrane segment and first extracellular segment. Both isoforms act as selective paracellular ion channels, either for anions (claudin-10a) or for cations (claudin-10b). Their diverse functions are reflected in completely different expression patterns in the body, especially in the kidney. Their structural and functional similarities and differences make them ideal subjects to study determinants of claudin charge selectivity and pore formation. This review aims to summarise research on permeability properties of the claudin-10 channels and their role in physiology and pathophysiology of the kidney.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.