Evidence map›Paper›PMID 27942869›Full record

ArticleDevelopment genes and evolution2017

Xenopus laevis neuronal cell adhesion molecule (nrcam): plasticity of a CAM in the developing nervous system.

Ashwin Lokapally, Sanjeeva Metikala, Thomas Hollemann

Abstract read
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In one paragraph

Article in Development genes and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Ashwin LokapallyInstitute for Physiological Chemistry, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Sanjeeva MetikalaInstitute for Physiological Chemistry, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.
Thomas HollemannInstitute for Physiological Chemistry, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany. thomas.hollemann@medizin.uni-halle.de.ORCID 0000-0002-5168-4540
Martin Luther University Halle-Wittenberg · DEMarine Biological Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuron-glial-related cell adhesion molecule (NRCAM) is a neuronal cell adhesion molecule of the L1 immunoglobulin superfamily, which plays diverse roles during nervous system development including axon growth and guidance, synapse formation, and formation of the myelinated nerve. Perturbations in NRCAM function cause a wide variety of disorders, which can affect wiring and targeting of neurons, or cause psychiatric disorders as well as cancers through abnormal modulation of signaling events. In the present study, we characterize the Xenopus laevis homolog of nrcam. Expression of Xenopus nrcam is most abundant along the dorsal midline throughout the developing brain and in the outer nuclear layer of the retina.

Indexed as

NeurogenesisAmino Acid SequenceAnimalsBrainCell Adhesion Molecules, NeuronalRetinaSequence AlignmentXenopus laevisXenopus ProteinsCell Adhesion Molecules, NeuronalNRCAM protein, XenopusXenopus ProteinsCell adhesion molecules (CAMs)Glial cellsNervous system developmentNeuronal cell adhesion molecule (nrcam)

Identifiers

PMID27942869
OpenAlexW2560092176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.