Evidence map›Paper›PMID 27942837›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2017

Refining prognosis in patients with hepatocellular carcinoma through incorporation of metabolic imaging biomarkers.

Satoshi Takeuchi, Eric M Rohren, Reham Abdel-Wahab, Lianchun Xiao, Jeffrey S Morris, Homer A Macapinlac, Manal M Hassan, Ahmed O Kaseb

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. The application ofQuantitative imaging in medicine and surgery · 2023
    Review
  2. Metabolic Tumor Volume Measured byJournal of hepatocellular carcinoma · 2023
    Article
  3. CMBD: a manually curated cancer metabolic biomarker knowledge database.Database : the journal of biological databases and curation · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Satoshi TakeuchiDepartment of Medical Oncology, Hokkaido University Graduate School of Medicine, North 15 West 7 Kita-ku, Sapporo, Japan.
Eric M RohrenDepartment of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1483, Houston, TX, 77030, USA.
Reham Abdel-WahabDepartment of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 426, Houston, TX, 77030, USA.
Lianchun XiaoDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1411, Houston, TX, 77030, USA.
Jeffrey S MorrisDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1411, Houston, TX, 77030, USA.
Homer A MacapinlacDepartment of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1483, Houston, TX, 77030, USA.
Manal M HassanDepartment of Radiology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA.
Ahmed O KasebDepartment of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 426, Houston, TX, 77030, USA. akaseb@mdanderson.org.
The University of Texas MD Anderson Cancer Center · USBaylor College of Medicine · USAssiut University Hospitals · EGHokkaido University · JP

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Molecular Epidemiology of Chronic Liver DiseasesK07CA106458 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI HASSAN, MANAL METWALLY · 2005 to 2009
$681k
Novel Point-of-Care Tool to Predict Response to Sorafenib in Hepatocellular CarcinomaR21CA190945 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KASEB, AHMED · 2016 to 2017
$383k
Integrating plasma IGF-1 into novel classification of hepatocellular carcinomaR21CA170035 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KASEB, AHMED · 2012 to 2013
$366k
NCI NIH HHS K07 CA106458NCI NIH HHS P30 CA016672NCI NIH HHS R21 CA170035NCI NIH HHS R21 CA190945
6 · The paper itself

Abstract

purpose

methodsWe retrospectively analyzed the records of patients with HCC who underwent FDG PET/CT before initial treatment from May 2013 through May 2014. Four PET/CT parameters were measured: maximum standardized uptake value (SUV

resultsThe analysis included 56 patients. Univariate analysis of the association between OS and continuous variables, including the PET/CT parameters SUV

conclusionPretreatment FDG PET/CT in patients with HCC can add to the prognostic value of standard clinical measures. Incorporation of imaging biomarkers derived from FDG PET/CT into HCC staging systems should be considered.

Indexed as

Positron Emission Tomography Computed TomographyAdultAgedAged, 80 and overBiomarkersCarcinoma, HepatocellularFemaleGlycolysisHumansLiver NeoplasmsMaleMiddle AgedNeoplasm StagingPrognosisRetrospective StudiesYoung AdultBiomarkersBCLC staging systemCLIP scoring systemFDG PET/CTHepatocellular carcinoma

Identifiers

PMID27942837
PMCPMC5400685
OpenAlexW2560575016

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.