ArticleEuropean biophysics journal : EBJ2017
Interpretation of amperometric kinetics of content release during contacts of vesicles with a lipid membrane.
Article in European biophysics journal : EBJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Generic prediction of exocytosis rate constants by size-based surface energies of nanoparticles and cells.Scientific reports · 2022Article
- Nanoparticles without and with protein corona: van der Waals and hydration interaction.Journal of biological physics · 2019Article
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1 author at 1 institution in 1 country.
Funding
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Abstract
The exocytotic pathway of secretion of molecules from cells includes transport by vesicles, tether-mediated fusion of vesicles with the plasma membrane accompanied by pore formation, and diffusion-mediated release of their contents via a pore to the outside. In related basic biophysical studies, vesicle-content release is tracked by measuring corresponding amperometric spikes. Although experiments of this type have a long history, the understanding of the underlying physics is still elusive. The present study elucidates the likely contribution of line energy, membrane tension and bending, osmotic pressure, hydration forces, and tethers to the potential energy for fusion-related pore formation and evolution. The overdamped Langevin equation is used to describe the pore dynamics, which are in turn employed to calculate the kinetics of content release and to interpret the shape of amperometric spikes.
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