Evidence map›Paper›PMID 27942539›Full record

ArticleOpen forum infectious diseases2016

Nocardiosis in the Tropical Northern Territory of Australia, 1997-2014.

Sarah L McGuinness, Sarah E Whiting, Rob Baird, Bart J Currie, Anna P Ralph, Nicholas M Anstey, Ric N Price, Joshua S Davis, Steven Y C Tong

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
8.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Article
  3. The genus Nocardia as a source of new antimicrobials.npj antimicrobials and resistance · 2025
    Review
  4. Article
  5. Frontiers in medicine · 2025
    Article
  6. First Documented Case of Pneumonia withInfection and drug resistance · 2025
    Article
  7. Severe pneumonia caused byFrontiers in medicine · 2025
    Article
  8. Epidemiology ofAntibiotics (Basel, Switzerland) · 2022
    Article
  9. Nocardiosis in Japan: a Multicentric Retrospective Cohort Study.Antimicrobial agents and chemotherapy · 2022
    Article
  10. Estradiol AggravateFrontiers in immunology · 2022
    Article
  11. Article
  12. Article
  13. Membranous Nephropathy Complicated with DisseminatedInfection and drug resistance · 2021
    Article
  14. Efficient differentiation ofJournal of medical microbiology · 2020
    Article
  15. Article
  16. Safety and Outcomes of Linezolid Use for Nocardiosis.Open forum infectious diseases · 2020
    Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Sarah L McGuinnessDepartment of Infectious Diseases and.
Sarah E WhitingDepartment of Infectious Diseases and.
Rob BairdDepartment of Infectious Diseases and; Territory Pathology, Royal Darwin Hospital, Darwin, Australia.
Bart J CurrieDepartment of Infectious Diseases and; Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Darwin, Australia.
Anna P RalphDepartment of Infectious Diseases and; Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Darwin, Australia.
Nicholas M AnsteyDepartment of Infectious Diseases and; Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Darwin, Australia.
Ric N PriceDepartment of Infectious Diseases and; Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Darwin, Australia;; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom.
Joshua S DavisGlobal and Tropical Health, Menzies School of Health Research, Charles Darwin University, Darwin, Australia;; Department of Infectious Diseases, John Hunter Hospital, Newcastle, Australia.
Steven Y C TongDepartment of Infectious Diseases and; Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Darwin, Australia.
Charles Darwin University · AUMenzies School of Health Research · AURoyal Darwin Hospital · AUUniversity of Oxford · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

background

methodsWe conducted a retrospective cohort study of nocardiosis diagnosed between 1997 and 2014. Population-based incidences were calculated using district population data.

resultsClinically significant nocardiosis was identified in 61 patients. The unadjusted population-based annual incidence of nocardiosis was 2.02 (95% confidence interval [CI], 1.55-2.60) per 100000 people and was 1.7 (95% CI, .96-2.90) fold higher in Indigenous compared with non-Indigenous persons (

conclusionsThe incidence of nocardiosis in tropical Australia is amongst the highest reported globally. Nocardiosis occurs in both immunocompromised and immunocompetent hosts, and it is associated with high rates of ICU admission, 1-year mortality, and resistance to commonly recommended antimicrobials. Diagnosis should be considered in patients with consistent clinical features, particularly if they are Indigenous or have chronic lung disease.

Indexed as

epidemiologyimmunocompromised hostNocardianocardiosistreatment.

Identifiers

PMID27942539
PMCPMC5144655
OpenAlexW2528999668

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.