ArticleNuclear receptor research2016
Xenobiotic Receptor-Mediated Regulation of Intestinal Barrier Function and Innate Immunity.
Article in Nuclear receptor research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06272240 (Study of the Role of the Tumor Microenvironment in Ovarian Cancer), which is not on this map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study of the Role of the Tumor Microenvironment in Ovarian Cancer
Who cites it
23 citing papers in PubMed, 35 citations in OpenAlex.
- Indole Propionic Acid Regulates Gut Immunity: Mechanisms of Metabolite-Driven Immunomodulation and Barrier Integrity.Journal of microbiology and biotechnology · 2025Review
- Integrating the gut microbiome and pharmacology.Science translational medicine · 2024Review
- Novel In Vitro Models for Cell Differentiation and Drug Transport Studies of the Human Intestine.Cells · 2023Article
- Stable isotope tracing in vivo reveals a metabolic bridge linking the microbiota to host histone acetylation.Cell reports · 2022Article
- How does Quorum Sensing of Intestinal Bacteria Affect Our Health and Mental Status?Microorganisms · 2022Review
- Nuclear Receptor Pathways Mediating the Development of Boar Taint.Metabolites · 2022Review
- Bacterial Indole as a Multifunctional Regulator of Klebsiella oxytoca Complex Enterotoxicity.mBio · 2022Article
- Bacterial and Viral Co-Infection in the Intestine: Competition Scenario and Their Effect on Host Immunity.International journal of molecular sciences · 2022Review
- Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and CAR on the gut microbiome using genetically modified mice.Acta pharmaceutica Sinica. B · 2022Article
- Dual Role of Indoles Derived From Intestinal Microbiota on Human Health.Frontiers in immunology · 2022Review
- The pregnane X receptor drives sexually dimorphic hepatic changes in lipid and xenobiotic metabolism in response to gut microbiota in mice.Microbiome · 2021Article
- Deciphering structural bases of intestinal and hepatic selectivity in targeting pregnane X receptor with indole-based microbial mimics.Bioorganic chemistry · 2021Article
- Aspergillus fumigatus tryptophan metabolic route differently affects host immunity.Cell reports · 2021Article
- Review
- Targeting the pregnane X receptor using microbial metabolite mimicry.EMBO molecular medicine · 2020Article
- The xenobiotic sensing pregnane X receptor regulates tissue damage and inflammation triggered by C difficile toxins.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- Tryptophan Co-Metabolism at the Host-Pathogen Interface.Frontiers in immunology · 2020Article
- Ammonia generation by tryptophan synthase drives a key genetic difference between genital and ocularProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Article
- Nuclear Receptors Regulate Intestinal Inflammation in the Context of IBD.Frontiers in immunology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
The molecular basis for the regulation of the intestinal barrier is a very fertile research area. A growing body of knowledge supports the targeting of various components of intestinal barrier function as means to treat a variety of diseases, including the inflammatory bowel diseases. Herein, we will summarize the current state of knowledge of
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.