Evidence map›Paper›PMID 27942452›Full record

ArticleNeuroImage. Clinical2017

CAG repeat length does not associate with the rate of cerebellar degeneration in spinocerebellar ataxia type 3.

Shang-Ran Huang, Yu-Te Wu, Chii-Wen Jao, Bing-Wen Soong, Jiing-Feng Lirng, Hsiu-Mei Wu, Po-Shan Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage. Clinical, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
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  6. Review
  7. Article
  8. Article
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  10. Article
  11. Article
  12. Article
  13. Article
  14. Network Reconfiguration Among Cerebellar Visual,Frontiers in aging neuroscience · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. MR Imaging of SCA3/MJD.Frontiers in neuroscience · 2020
    Review
  19. Article
  20. Neuroradiological Findings in the Spinocerebellar Ataxias.Tremor and other hyperkinetic movements (New York, N.Y.) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shang-Ran HuangDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, No.155, Sec. 2, Linong St., Taipei, Taiwan.
Yu-Te WuDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, No.155, Sec. 2, Linong St., Taipei, Taiwan; Institute of Biophotonics, National Yang-Ming University, No.155, Sec. 2, Linong St., Taipei, Taiwan.
Chii-Wen JaoInstitute of Biophotonics, National Yang-Ming University, No.155, Sec. 2, Linong St., Taipei, Taiwan.
Bing-Wen SoongDepartment of Neurology, Neurological Institute, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Taipei, Taiwan; School of Medicine, National Yang-Ming University, No.155, Sec. 2, Linong St., Taipei, Taiwan.
Jiing-Feng LirngSchool of Medicine, National Yang-Ming University, No.155, Sec. 2, Linong St., Taipei, Taiwan; Department of Radiology, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Taipei, Taiwan.
Hsiu-Mei WuSchool of Medicine, National Yang-Ming University, No.155, Sec. 2, Linong St., Taipei, Taiwan; Department of Radiology, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Taipei, Taiwan.
Po-Shan WangInstitute of Biophotonics, National Yang-Ming University, No.155, Sec. 2, Linong St., Taipei, Taiwan; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Taipei, Taiwan; School of Medicine, National Yang-Ming University, No.155, Sec. 2, Linong St., Taipei, Taiwan; Department of Neurology, Taipei Municipal Gan-Dau Hospital, No.12, Ln. 225, Zhixing Rd., Taipei, Taiwan.
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This cross-sectional study investigated the correlation between the CAG repeat length and the degeneration of cerebellum in spinocerebellar ataxia type 3 (SCA3) patients based on neuroimaging approaches. Forty SCA3 patients were recruited and classified into two subgroups according to their CAG repeat lengths (≥ 74 and < 74). We measured each patient's Scale for the Assessment and Rating of Ataxia (SARA) score,

Indexed as

CerebellumMachado-Joseph DiseaseTrinucleotide RepeatsAdultAgedAspartic AcidCreatineCross-Sectional StudiesFemaleHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleMiddle AgedSeverity of Illness IndexAspartic AcidCreatineN-acetylaspartateBrain connectivityFractal dimensionMagnetic resonance imagingMagnetic resonance spectroscopyNAASCA3

Identifiers

PMID27942452
PMCPMC5133648
OpenAlexW2551920515

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.