Evidence map›Paper›PMID 27941950›Full record

ArticleScientific reports2016

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice.

Juliane Weiner, Mathias Kranz, Nora Klöting, Anne Kunath, Karen Steinhoff, Eddy Rijntjes, Josef Köhrle, Vilia Zeisig, Mohammed Hankir, Claudia Gebhardt and 10 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 87 citations in OpenAlex.

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  4. Thyroid Hormone Effects on Glucose Disposal in Patients With Insulin Receptor Mutations.The Journal of clinical endocrinology and metabolism · 2020
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  17. International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 5 institutions in 1 country.

Juliane WeinerDepartment of Endocrinology and Nephrology, University Hospital, Leipzig, Germany.
Mathias KranzHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Research Site Leipzig, Department of Neuroradiopharmaceuticals, Leipzig, Germany.
Nora KlötingDepartment of Endocrinology and Nephrology, University Hospital, Leipzig, Germany.
Anne KunathGerman Center for Diabetes Research (DZD), Leipzig, Germany.
Karen SteinhoffDepartment of Nuclear Medicine, University Hospital, Leipzig, Germany.
Eddy RijntjesInstitute of Experimental Endocrinology, Charité University Hospital, Berlin, Germany.
Josef KöhrleInstitute of Experimental Endocrinology, Charité University Hospital, Berlin, Germany.
Vilia ZeisigDepartment of Nuclear Medicine, University Hospital, Leipzig, Germany.
Mohammed HankirUniversity of Leipzig, IFB Adiposity Diseases, Leipzig, Germany.
Claudia GebhardtDepartment of Endocrinology and Nephrology, University Hospital, Leipzig, Germany.
Winnie Deuther-ConradHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Research Site Leipzig, Department of Neuroradiopharmaceuticals, Leipzig, Germany.
John T HeikerDepartment of Endocrinology and Nephrology, University Hospital, Leipzig, Germany.
Susan KralischDepartment of Endocrinology and Nephrology, University Hospital, Leipzig, Germany.
Michael StumvollDepartment of Endocrinology and Nephrology, University Hospital, Leipzig, Germany.
Matthias BlüherDepartment of Endocrinology and Nephrology, University Hospital, Leipzig, Germany.
Osama SabriUniversity of Leipzig, IFB Adiposity Diseases, Leipzig, Germany.
Swen HesseUniversity of Leipzig, IFB Adiposity Diseases, Leipzig, Germany.
Peter BrustHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Research Site Leipzig, Department of Neuroradiopharmaceuticals, Leipzig, Germany.
Anke TönjesDepartment of Endocrinology and Nephrology, University Hospital, Leipzig, Germany.
Kerstin KrauseDepartment of Endocrinology and Nephrology, University Hospital, Leipzig, Germany.
University Hospital Leipzig · DEIFB Adiposity Diseases · DEHelmholtz-Zentrum Dresden-Rossendorf · DECharité - Universitätsmedizin Berlin · DEHeinrich Heine University Düsseldorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to determine the effect of thyroid hormone dysfunction on brown adipose tissue activity and white adipose tissue browning in mice. Twenty randomized female C57BL/6NTac mice per treatment group housed at room temperature were rendered hypothyroid or hyperthyroid. In-vivo small animal

Indexed as

AdipocytesAdipose Tissue, BrownAdipose Tissue, WhiteAnimalsFemaleFluorodeoxyglucose F18Gene Expression RegulationHyperthyroidismHypothyroidismMagnetic Resonance ImagingMiceMice, Inbred C57BLPropylthiouracilRandom AllocationSignal TransductionThermogenesisFluorodeoxyglucose F18PropylthiouracilThyroxine

Identifiers

PMID27941950
PMCPMC5150531
OpenAlexW2567630503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.