Basic research: Killing the old: cell senescence in atherosclerosis.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

16 citing papers in PubMed.

1. The role of cellular senescence in cardiovascular disease.Cell death discovery · 2025
   Review
2. The potential of flavonoids to mitigate cellular senescence in cardiovascular disease.Biogerontology · 2024
   Review
3. LARP7 overexpression alleviates aortic senescence and atherosclerosis.Journal of cellular and molecular medicine · 2024
   Article
4. Cells in Atherosclerosis: Focus on Cellular Senescence from Basic Science to Clinical Practice.International journal of molecular sciences · 2023
   Review
5. Senescent Cells: A Therapeutic Target in Cardiovascular Diseases.Cells · 2023
   Review
6. Targeted elimination of senescent cells by engineered extracellular vesicles attenuates atherosclerosis in ApoETheranostics · 2023
   Article
7. The multifaceted role of the SASP in atherosclerosis: from mechanisms to therapeutic opportunities.Cell & bioscience · 2022
   Review
8. Cellular Senescence and Ageing: Mechanisms and Interventions.Frontiers in aging · 2022
   Review
9. Therapeutic and diagnostic targeting of fibrosis in metabolic, proliferative and viral disorders.Advanced drug delivery reviews · 2021
   Review
10. Role of MicroRNA-145 in DNA Damage Signalling and Senescence in Vascular Smooth Muscle Cells of Type 2 Diabetic Patients.Cells · 2021
    Article
11. Ageing and atherosclerosis: vascular intrinsic and extrinsic factors and potential role of IL-6.Nature reviews. Cardiology · 2021
    Review
12. Time-dependent replicative senescence vs. disturbed flow-induced pre-mature aging in atherosclerosis.Redox biology · 2020
    Review
13. Inflammatory Drivers of Cardiovascular Disease: Molecular Characterization of Senescent Coronary Vascular Smooth Muscle Cells.Frontiers in physiology · 2020
    Article
14. CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells.Molecular medicine reports · 2019
    Article
15. Synaptotagmin-7, a binding protein of P53, inhibits the senescence and promotes the tumorigenicity of lung cancer cells.Bioscience reports · 2019
    Article
16. p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli.Aging · 2017
    Article

Corrections and comments

• Comment on
  Senescent intimal foam cells are deleterious at all stages of atherosclerosis.2016
• Erratum issued
  Killing the old: cell senescence in atherosclerosis.2017

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

Indexed as