Evidence map›Paper›PMID 27941776›Full record

Trial reportBone marrow transplantation2017

Low-dose alemtuzumab for GvHD prevention followed by prophylactic donor lymphocyte infusions in high-risk leukemia.

P Tsirigotis, M Liga, K Gkirkas, M Stamouli, E Triantafyllou, M Marangos, I Pessach, A Sarantopoulos, N Spyridis, A Spyridonidis

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Bone marrow transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

P TsirigotisBMT Unit, Department of Internal Medicine, 'Attikon' University Hospital of Athens, Athens, Greece.
M LigaBMT Unit, Department of Internal Medicine, University Hospital of Patras, Rio, Greece.
K GkirkasBMT Unit, Department of Internal Medicine, 'Attikon' University Hospital of Athens, Athens, Greece.
M StamouliBMT Unit, Department of Internal Medicine, 'Attikon' University Hospital of Athens, Athens, Greece.
E TriantafyllouBMT Unit, Department of Internal Medicine, University Hospital of Patras, Rio, Greece.
M MarangosBMT Unit, Department of Internal Medicine, University Hospital of Patras, Rio, Greece.
I PessachBMT Unit, Department of Internal Medicine, 'Attikon' University Hospital of Athens, Athens, Greece.
A SarantopoulosBMT Unit, Department of Internal Medicine, University Hospital of Patras, Rio, Greece.
N SpyridisBMT Unit, Department of Internal Medicine, University Hospital of Patras, Rio, Greece.
A SpyridonidisBMT Unit, Department of Internal Medicine, University Hospital of Patras, Rio, Greece.
General University Hospital of Patras · GRUniversity General Hospital Attikon · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We analyzed the use of low-dose alemtuzumab in a cohort of 158 consecutive patients who underwent allogeneic PBSC transplantation. Patients with high-risk acute leukemia were prospectively screened for prophylactic donor lymphocyte infusion (pDLI). Lymphocytes were administered repeatedly at low and non-escalating doses (0.5-1 × 10

Indexed as

AllograftsGraft vs Host DiseaseHematopoietic Stem Cell TransplantationLeukemiaLymphocyte TransfusionSiblingsUnrelated DonorsAdolescentAdultAgedAlemtuzumabDisease-Free SurvivalFemaleHumansMaleMiddle AgedAlemtuzumab

Identifiers

PMID27941776
OpenAlexW2567541501

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.